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Open AccessArticle

Disposable Optical Stretcher Fabricated by Microinjection Moulding

1
Institute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing, National Research Council, 70124 Bari, Italy
2
Institute for Photonics and Nanotechnologies, National Research Council, 20133 Milan, Italy
3
Institute for Photonics and Nanotechnologies, National Research Council, 70126 Bari, Italy
4
Institute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing, National Research Council, 20133 Milan, Italy
*
Author to whom correspondence should be addressed.
Micromachines 2018, 9(8), 388; https://doi.org/10.3390/mi9080388
Received: 6 July 2018 / Revised: 27 July 2018 / Accepted: 1 August 2018 / Published: 4 August 2018
(This article belongs to the Special Issue Optical Manipulation of Cells: Strategies and Devices)
Microinjection moulding combined with the use of removable inserts is one of the most promising manufacturing processes for microfluidic devices, such as lab-on-chip, that have the potential to revolutionize the healthcare and diagnosis systems. In this work, we have designed, fabricated and tested a compact and disposable plastic optical stretcher. To produce the mould inserts, two micro manufacturing technologies have been used. Micro electro discharge machining (µEDM) was used to reproduce the inverse of the capillary tube connection characterized by elevated aspect ratio. The high accuracy of femtosecond laser micromachining (FLM) was exploited to manufacture the insert with perfectly aligned microfluidic channels and fibre slots, facilitating the final composition of the optical manipulation device. The optical stretcher operation was tested using microbeads and red blood cells solutions. The prototype presented in this work demonstrates the feasibility of this approach, which should guarantee real mass production of ready-to-use lab-on-chip devices. View Full-Text
Keywords: microfluidics; microinjection moulding; femtosecond laser micromachining; optical manipulation microfluidics; microinjection moulding; femtosecond laser micromachining; optical manipulation
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MDPI and ACS Style

Trotta, G.; Martínez Vázquez, R.; Volpe, A.; Modica, F.; Ancona, A.; Fassi, I.; Osellame, R. Disposable Optical Stretcher Fabricated by Microinjection Moulding. Micromachines 2018, 9, 388.

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