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Micromachines 2017, 8(3), 87;

Advances in Single Cell Impedance Cytometry for Biomedical Applications

Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore
Author to whom correspondence should be addressed.
Academic Editors: Weihua Li, Hengdong Xi and Say Hwa Tan
Received: 31 January 2017 / Revised: 27 February 2017 / Accepted: 7 March 2017 / Published: 12 March 2017
(This article belongs to the Special Issue Insights and Advancements in Microfluidics)
Full-Text   |   PDF [8768 KB, uploaded 12 March 2017]   |  


Microfluidics impedance cytometry is an emerging research tool for high throughput analysis of dielectric properties of cells and internal cellular components. This label-free method can be used in different biological assays including particle sizing and enumeration, cell phenotyping and disease diagnostics. Herein, we review recent developments in single cell impedance cytometer platforms, their biomedical and clinical applications, and discuss the future directions and challenges in this field. View Full-Text
Keywords: impedance spectroscopy; flow cytometry; single cell analysis impedance spectroscopy; flow cytometry; single cell analysis

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Petchakup, C.; Li, K.H.H.; Hou, H.W. Advances in Single Cell Impedance Cytometry for Biomedical Applications. Micromachines 2017, 8, 87.

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