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Review

Microfluidics-Based POCT for SARS-CoV-2 Diagnostics

by 1,*, 1, 1 and 2,*
1
School of Mechanical Engineering, Yangzhou University, Yangzhou 225127, China
2
College of Food and Biological Engineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China
*
Authors to whom correspondence should be addressed.
Academic Editors: Trieu Nguyen and Mehmet Remzi Dokmeci
Micromachines 2022, 13(8), 1238; https://doi.org/10.3390/mi13081238
Received: 15 June 2022 / Revised: 30 July 2022 / Accepted: 30 July 2022 / Published: 1 August 2022
(This article belongs to the Special Issue Point-of-Care Devices for Pathogen Detection)
A microfluidic chip is a tiny reactor that can confine and flow a specific amount of fluid into channels of tens to thousands of microns as needed and can precisely control fluid flow, pressure, temperature, etc. Point-of-care testing (POCT) requires small equipment, has short testing cycles, and controls the process, allowing single or multiple laboratory facilities to simultaneously analyze biological samples and diagnose infectious diseases. In general, rapid detection and stage assessment of viral epidemics are essential to overcome pandemic situations and diagnose promptly. Therefore, combining microfluidic devices with POCT improves detection efficiency and convenience for viral disease SARS-CoV-2. At the same time, the POCT of microfluidic chips increases user accessibility, improves accuracy and sensitivity, shortens detection time, etc., which are beneficial in detecting SARS-CoV-2. This review shares recent advances in POCT-based testing for COVID-19 and how it is better suited to help diagnose in response to the ongoing pandemic. View Full-Text
Keywords: microfluidic; SARS-CoV-2; point of care testing microfluidic; SARS-CoV-2; point of care testing
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MDPI and ACS Style

Yin, B.; Wan, X.; Sohan, A.S.M.M.F.; Lin, X. Microfluidics-Based POCT for SARS-CoV-2 Diagnostics. Micromachines 2022, 13, 1238. https://doi.org/10.3390/mi13081238

AMA Style

Yin B, Wan X, Sohan ASMMF, Lin X. Microfluidics-Based POCT for SARS-CoV-2 Diagnostics. Micromachines. 2022; 13(8):1238. https://doi.org/10.3390/mi13081238

Chicago/Turabian Style

Yin, Binfeng, Xinhua Wan, A. S. M. Muhtasim Fuad Sohan, and Xiaodong Lin. 2022. "Microfluidics-Based POCT for SARS-CoV-2 Diagnostics" Micromachines 13, no. 8: 1238. https://doi.org/10.3390/mi13081238

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