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Microfluidic Systems Applied in Solid-State Nanopore Sensors

State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China
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Micromachines 2020, 11(3), 332; https://doi.org/10.3390/mi11030332
Received: 19 February 2020 / Revised: 8 March 2020 / Accepted: 20 March 2020 / Published: 23 March 2020
(This article belongs to the Special Issue Biomedical Microfluidic Devices 2019)
Microfluidic system, as a kind of miniature integrated operating platform, has been applied to solid-state nanopore sensors after many years of experimental study. In the process of introducing microfluidic into solid-state nanopore sensors, many novel device structures are designed due to the abundance of analytes and the diversity of detection methods. Here we review the fundamental setup of nanopore-based microfluidic systems and the developments and advancements that have been taking place in the field. The microfluidic systems with a multichannel strategy to elevate the throughput and efficiency of nanopore sensors are then presented. Multifunctional detection represented by optical-electrical detection, which is realized by microfluidic integration, is also described. A high integration microfluidic system with nanopore is further discussed, which shows the prototype of commercialization. View Full-Text
Keywords: solid-state nanopore; microfluidic system; multichannel; optical detection; integration solid-state nanopore; microfluidic system; multichannel; optical detection; integration
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MDPI and ACS Style

Fu, J.; Wu, L.; Qiao, Y.; Tu, J.; Lu, Z. Microfluidic Systems Applied in Solid-State Nanopore Sensors. Micromachines 2020, 11, 332.

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