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Communication

Dietary Supplements Based on Red Yeast Rice—A Source of Citrinin?

Department of Physiology and Toxicology, Faculty of Biological Sciences, Kazimierz Wielki University, 30 Chodkiewicza Street, 85-064 Bydgoszcz, Poland
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Toxins 2021, 13(7), 497; https://doi.org/10.3390/toxins13070497
Received: 29 June 2021 / Revised: 14 July 2021 / Accepted: 15 July 2021 / Published: 17 July 2021
(This article belongs to the Special Issue Mycotoxin Contamination and Food Safety)
Citrinin (CIT) is secondary metabolite of filamentous molds. This mycotoxin has nephrotoxic, hepatotoxic, embryocidal, and fetotoxic properties. It is also produced by several species of the three genera Penicillium spp., Aspergillus spp., and Monascus spp., which are used to make red yeast rice (RYR). The material for this study consisted of 15 dietary supplements containing an extract of fermented red rice, available on the Polish market. Samples were extracted using a MeOH–H2O mixture, cleaned-up with an immunoaffinity CitriTest HPLC column, and quantified by HPLC–FLD. None of the analyzed samples contained CIT above the established limit of detection (LOD). Studies on the presence of toxic metabolites in red yeast rice show the importance of regulating this product and of clear information on the label regarding the standardized amounts of monacolin. View Full-Text
Keywords: mycotoxin; CIT; contamination; dietary supplements; red yeast rice mycotoxin; CIT; contamination; dietary supplements; red yeast rice
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MDPI and ACS Style

Twarużek, M.; Ałtyn, I.; Kosicki, R. Dietary Supplements Based on Red Yeast Rice—A Source of Citrinin? Toxins 2021, 13, 497. https://doi.org/10.3390/toxins13070497

AMA Style

Twarużek M, Ałtyn I, Kosicki R. Dietary Supplements Based on Red Yeast Rice—A Source of Citrinin? Toxins. 2021; 13(7):497. https://doi.org/10.3390/toxins13070497

Chicago/Turabian Style

Twarużek, Magdalena, Iwona Ałtyn, and Robert Kosicki. 2021. "Dietary Supplements Based on Red Yeast Rice—A Source of Citrinin?" Toxins 13, no. 7: 497. https://doi.org/10.3390/toxins13070497

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