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Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species

Department of Animal Science, North Carolina State University, Raleigh, NC 27607, USA
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Toxins 2019, 11(6), 364; https://doi.org/10.3390/toxins11060364
Received: 31 May 2019 / Revised: 13 June 2019 / Accepted: 14 June 2019 / Published: 21 June 2019
(This article belongs to the Special Issue Biological Activities of Alkaloids: From Toxicology to Pharmacology)
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Abstract

Fescue toxicosis is a multifaceted syndrome that elicits many negative effects on livestock consuming ergot alkaloids produced by endophyte-infected tall fescue. The economic losses associated with fescue toxicosis are primarily due to reproductive failure including altered cyclicity, suppressed hormone secretion, reduced pregnancy rates, agalactia, and reduced offspring birth weights. For decades, a multitude of research has investigated the physiological and cellular mechanisms of these reproductive failures associated with fescue toxicosis. This review will summarize the various effects of ergot alkaloids on female reproduction in grazing livestock species. View Full-Text
Keywords: ergot alkaloids; livestock; reproduction ergot alkaloids; livestock; reproduction
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Poole, R.K.; Poole, D.H. Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species. Toxins 2019, 11, 364.

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