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Toxins 2018, 10(4), 143;

Antipruritic Effects of Botulinum Neurotoxins

Department of Health Science and Technology, Aalborg University, Frederik Bajers Vej 7A2, A2-208, 9220 Aalborg East, Denmark
Received: 5 March 2018 / Revised: 27 March 2018 / Accepted: 27 March 2018 / Published: 29 March 2018
Full-Text   |   PDF [379 KB, uploaded 3 May 2018]


This review explores current evidence to demonstrate that botulinum neurotoxins (BoNTs) exert antipruritic effects. Both experimental and clinical conditions in which botulinum neurotoxins have been applied for pruritus relief will be presented and significant findings will be highlighted. Potential mechanisms underlying antipruritic effects will also be discussed and ongoing challenges and unmet needs will be addressed. View Full-Text
Keywords: botulinum neurotoxins; itch; pruritus; antipruritic; clinical; experimental botulinum neurotoxins; itch; pruritus; antipruritic; clinical; experimental
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Gazerani, P. Antipruritic Effects of Botulinum Neurotoxins. Toxins 2018, 10, 143.

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