First Report on the Occurrence of Tetrodotoxins in Bivalve Mollusks in The Netherlands
Abstract
:1. Introduction
2. Results
2.1. Sanitary Survey Results
2.2. Verfication of the Results Obtained
3. Discussion
4. Conclusions
5. Materials and Methods
5.1. Reagents and Standards
5.2. Preperation of Extracts
5.3. TTX LC-MS/MS Analysis
5.4. LC-Q-Exactive Orbitrap Screening TTX Analogues
5.5. Neuroblastoma Assay
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Gerssen, A.; Bovee, T.H.F.; Klijnstra, M.D.; Poelman, M.; Portier, L.; Hoogenboom, R.L.A.P. First Report on the Occurrence of Tetrodotoxins in Bivalve Mollusks in The Netherlands. Toxins 2018, 10, 450. https://doi.org/10.3390/toxins10110450
Gerssen A, Bovee THF, Klijnstra MD, Poelman M, Portier L, Hoogenboom RLAP. First Report on the Occurrence of Tetrodotoxins in Bivalve Mollusks in The Netherlands. Toxins. 2018; 10(11):450. https://doi.org/10.3390/toxins10110450
Chicago/Turabian StyleGerssen, Arjen, Toine H. F. Bovee, Mirjam D. Klijnstra, Marnix Poelman, Liza Portier, and Ron L. A. P. Hoogenboom. 2018. "First Report on the Occurrence of Tetrodotoxins in Bivalve Mollusks in The Netherlands" Toxins 10, no. 11: 450. https://doi.org/10.3390/toxins10110450