Fructose Containing Sugars at Normal Levels of Consumption Do Not Effect Adversely Components of the Metabolic Syndrome and Risk Factors for Cardiovascular Disease

Angelopoulos, Theodore J.; Lowndes, Joshua; Sinnett, Stephanie; Rippe, James M.

doi:10.3390/nu8040179

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Fructose Containing Sugars at Normal Levels of Consumption Do Not Effect Adversely Components of the Metabolic Syndrome and Risk Factors for Cardiovascular Disease

Theodore J. Angelopoulos

^1,*,

Joshua Lowndes

²,

Stephanie Sinnett

² and

James M. Rippe

^2,3,4

Obesity Research Center, School of Health Sciences, Emory & Henry College, 601 Radio Hill Rd, Marion, VA 24354, USA

Rippe Lifestyle Institute of Florida, 215 Celebration Place, Celebration, FL 34747, USA

Rippe Lifestyle Institute, 21 North Quinsigamond Avenue, Shrewsbury, MA 01545, USA

⁴

Biomedical Sciences, University of Central Florida, 4000 Central Florida Boulevard, Orlando, FL 32816, USA

Author to whom correspondence should be addressed.

Nutrients 2016, 8(4), 179; https://doi.org/10.3390/nu8040179

Received: 13 July 2015 / Accepted: 10 March 2016 / Published: 23 March 2016

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Abstract

The objective of the current study was to explore our hypothesis that average consumption of fructose and fructose containing sugars would not increase risk factors for cardiovascular disease (CVD) and the metabolic syndrome (MetS). A randomized, double blind, parallel group study was conducted where 267 individuals with BMI between 23 and 35 kg/m² consumed low fat sugar sweetened milk, daily for ten weeks as part of usual weight-maintenance diet. One group consumed 18% of calories from high fructose corn syrup (HFCS), another group consumed 18% of calories from sucrose, a third group consumed 9% of calories from fructose, and the fourth group consumed 9% of calories from glucose. There was a small change in waist circumference (80.9 ± 9.5 vs. 81.5 ± 9.5 cm) in the entire cohort, as well as in total cholesterol (4.6 ± 1.0 vs. 4.7 ± 1.0 mmol/L, p < 0.01), triglycerides (TGs) (11.5 ± 6.4 vs. 12.6 ± 8.9 mmol/L, p < 0.01), and systolic (109.2 ± 10.2 vs. 106.1 ± 10.4 mmHg, p < 0.01) and diastolic blood pressure (69.8 ± 8.7 vs. 68.1 ± 9.7 mmHg, p < 0.01). The effects of commonly consumed sugars on components of the MetS and CVD risk factors are minimal, mixed and not clinically significant. View Full-Text

Keywords: fructose; high fructose corn syrup; sucrose; metabolic syndrome; cardiovascular disease

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MDPI and ACS Style

Angelopoulos, T.J.; Lowndes, J.; Sinnett, S.; Rippe, J.M. Fructose Containing Sugars at Normal Levels of Consumption Do Not Effect Adversely Components of the Metabolic Syndrome and Risk Factors for Cardiovascular Disease. Nutrients 2016, 8, 179. https://doi.org/10.3390/nu8040179

AMA Style

Angelopoulos TJ, Lowndes J, Sinnett S, Rippe JM. Fructose Containing Sugars at Normal Levels of Consumption Do Not Effect Adversely Components of the Metabolic Syndrome and Risk Factors for Cardiovascular Disease. Nutrients. 2016; 8(4):179. https://doi.org/10.3390/nu8040179

Chicago/Turabian Style

Angelopoulos, Theodore J., Joshua Lowndes, Stephanie Sinnett, and James M. Rippe 2016. "Fructose Containing Sugars at Normal Levels of Consumption Do Not Effect Adversely Components of the Metabolic Syndrome and Risk Factors for Cardiovascular Disease" Nutrients 8, no. 4: 179. https://doi.org/10.3390/nu8040179

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Fructose Containing Sugars at Normal Levels of Consumption Do Not Effect Adversely Components of the Metabolic Syndrome and Risk Factors for Cardiovascular Disease

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