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Nutritional Solutions to Reduce Risks of Negative Health Impacts of Air Pollution

DSM Nutritional Products Ltd., Wurmisweg 576, Kaiseraugst 4303, Switzerland
Division of Allergy, Pulmonary and Critical Care Medicine, NW628 UPMC Montefiore Hospital, University of Pittsburgh Medical Center, 3459 Fifth Avenue, Pittsburgh, PA 15213, USA
Centre for Asthma and Respiratory Diseases, University of Newcastle, Level 2, West Wing, HMRI Building, Kookaburra Crt, New Lambton Heights, NSW 2305, Australia
Department of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, Bridgeside Point I, 100 Technology Drive Room 350, Pittsburgh, PA 15219-3130, USA
Pannónia Street 66, Budapest 1133, Hungary
Author to whom correspondence should be addressed.
Nutrients 2015, 7(12), 10398-10416;
Received: 17 September 2015 / Revised: 22 November 2015 / Accepted: 2 December 2015 / Published: 10 December 2015
PDF [710 KB, uploaded 10 December 2015]


Air pollution worldwide has been associated with cardiovascular and respiratory morbidity and mortality, particularly in urban settings with elevated concentrations of primary pollutants. Air pollution is a very complex mixture of primary and secondary gases and particles, and its potential to cause harm can depend on multiple factors—including physical and chemical characteristics of pollutants, which varies with fine-scale location (e.g., by proximity to local emission sources)—as well as local meteorology, topography, and population susceptibility. It has been hypothesized that the intake of anti-oxidant and anti-inflammatory nutrients may ameliorate various respiratory and cardiovascular effects of air pollution through reductions in oxidative stress and inflammation. To date, several studies have suggested that some harmful effects of air pollution may be modified by intake of essential micronutrients (such as B vitamins, and vitamins C, D, and E) and long-chain polyunsaturated fatty acids. Here, we review the existing literature related to the potential for nutrition to modify the health impacts of air pollution, and offer a framework for examining these interactions. View Full-Text
Keywords: air pollution; oxidative stress; inflammation; nutrients; vitamins; polyunsaturated fatty acids air pollution; oxidative stress; inflammation; nutrients; vitamins; polyunsaturated fatty acids

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MDPI and ACS Style

Péter, S.; Holguin, F.; Wood, L.G.; Clougherty, J.E.; Raederstorff, D.; Antal, M.; Weber, P.; Eggersdorfer, M. Nutritional Solutions to Reduce Risks of Negative Health Impacts of Air Pollution. Nutrients 2015, 7, 10398-10416.

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