Leader-Inspired Nutrition: Promoting Safe Dietary Supplement Use for Service Members
Abstract
1. Introduction
- “Natural anabolic agent for explosive strength and power”
- “Clinically proven fat burner for healthy and safe weight loss”
- “Uniquely effective at relieving pain & enhancing mood”
2. Leader-Inspired Nutrition for Promoting Safe Supplement Use
3. Key Strategic Imperatives
3.1. Strategic Imperative I: Provide Education and Training Opportunities as Required by DoDI 6130.06
3.2. Strategic Imperative II: Disseminate Key Messages on Dietary Supplement Safety
- FDA does not evaluate dietary supplement products for safety, quality, or effectiveness before they enter the market. Dietary supplements are intended to supplement the diet. They are not substitutes for a healthy, balanced eating plan.
- According to DoDI 6130.06, Service Members are not allowed to use dietary supplements with prohibited ingredients.
- Dietary supplements may contain ingredients not listed on the Supplement Facts label.
- If Service Members choose to use a dietary supplement, they should look for products that carry a reputable third-party certification seal, such as Banned Substances Control Group (BSCG) Certified Drug Free, LGC’s Informed Sport, National Sanitation Foundation International (NSF) Certified Sport, and United States Pharmacopeia (USP) verified.
- Third-party certification does not guarantee a dietary supplement is safe or effective, but will ensure the product contains what is listed on the label, thereby reducing the risk of consuming potentially unsafe or prohibited ingredients and reducing the chance of a positive DoD drug test.
3.3. Strategic Imperative III: Model and Reinforce Responsible Dietary Supplement Use
- Do performance dietitians or other health professionals have concerns that can be addressed during these rounds?
- What do Service Members need to achieve their personal health goals and maintain overall well-being?
- How do they assist Service Members with questions about dietary supplements and performance products?
- Do they know where to go for credible, evidence-based information?
3.4. Strategic Imperative IV: Assess the Dietary Supplement Environment on Base
- Are there posters and advertisements that are misleading?
- Is there an opportunity for OPSS educational materials to be displayed to help Service Members choose safe supplements? Is there an opportunity to engage with the on-base retail establishments to have them display OPSS resources?
- Is there an opportunity to engage OPSS with leaders on base to ensure resources are distributed?
- Leaders can work with OPSS, other leaders, and on-base retail establishments to assess whether a sufficient number of dietary supplement products available on store shelves have been third-party certified by organizations such as BSCG Certified Drug Free, LGC’s Informed Sport, or NSF Certified Sport.
3.5. Strategic Imperative V: Encourage All Personnel to Use the OPSS Website at OPSS.org
3.5.1. What Resources and Tools Can Leaders Leverage?
- Evidence-based content: OPSS produces a variety of evidence-based content, including articles, videos, handouts, and infographics, all publicly available on OPSS.org. Content development priorities are guided by input from the Services, inquiries from Service Members via the Ask the Expert portal, working partnerships, and market analyses of trending dietary supplement ingredients. The OPSS Team monitors and investigates potentially dangerous products and ingredients marketed as dietary supplements. Additionally, OPSS evaluates the efficacy and safety of dietary supplement ingredients to optimize performance and promote overall health. The resulting information is used to develop evidence-based educational materials and services, empowering Service Members to make informed and safe dietary supplement decisions.
- DoD Prohibited Dietary Supplement Ingredients List: In accordance with DoDI 6130.06, the OPSS website provides a database of dietary supplement ingredients prohibited by the DoD to help Service Members know what to avoid when considering dietary supplement products [16]. The database is updated quarterly, or when an FDA action occurs or new scientific information becomes available regarding dietary supplement ingredients. The OPSS Team creates content and resources to raise awareness of prohibited ingredients and continually strives to improve search functionality for all prohibited ingredients and their “other names” that may appear on product Supplement Facts labels.
- The OPSS Scorecard: The Scorecard, or “algorithm,” was created to assist all consumers in making an informed decision about dietary supplement products [34]. It guides users through a rapid screening process, promoting a thorough review of product labels before making a purchase. By answering seven “yes” or “no” questions on topics related to third-party certification, multiple ingredient combinations, proprietary blends, and questionable claims, Service Members can determine whether a product might be risky. However, the initial step should always involve checking the DoD Prohibited Dietary Supplement Ingredients List [16]. If a product label lists a prohibited ingredient, there is no reason to score the product, as Service Members should not purchase such products.
- Ask the Expert: Service Members, family members, leaders, providers, Veterans, allied health professionals, and all consumers can visit the Ask the Expert portal on OPSS.org to submit questions about anything related to dietary supplements and performance products and receive evidence-based responses from the OPSS Team within two weeks. All information is treated as confidential [35].
3.5.2. Presentations and Trainings
3.5.3. Outreach
3.5.4. Partnerships
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- US Department of Defense. Use of Dietary Supplements in the DoD. Available online: www.opss.org/sites/default/files/2022-03/DoDI_6130_06_Use_of_Dietary_Supplements_in_the_DoD_508.pdf (accessed on 9 October 2025).
- Knapik, J.J.; Trone, D.W.; Steelman, R.A.; Farina, E.K.; Lieberman, H.R. Prevalence of and Factors Associated with Dietary Supplement Use in a Stratified, Random Sample of US Military Personnel: The US Military Dietary Supplement Use Study. J. Nutr. 2021, 151, 3495–3506. [Google Scholar] [CrossRef]
- Tucker, J.; Fischer, T.; Upjohn, L.; Mazzera, D.; Kumar, M. Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated with US Food and Drug Administration Warnings. JAMA Netw. Open 2018, 1, e183337. [Google Scholar] [CrossRef]
- Deuster, P.A. Dietary Supplements and Adverse Events. Mil. Med. 2020, 185, e1381–e1382. [Google Scholar] [CrossRef] [PubMed]
- Humphreys, M.A.; Phillips, C.J.; Trone, D.W. Association Between Dietary Supplement Use and ICD-9-CM Code Classification in Active Duty US Navy and Marine Corps Service Members. Mil. Med. 2019, 184, e531–e537. [Google Scholar] [CrossRef] [PubMed]
- Knapik, J.J.; Trone, D.W.; Steelman, R.A.; Farina, E.K.; Lieberman, H.R. Adverse Effects Associated with Multiple Categories of Dietary Supplements: The Military Dietary Supplement Use Study. J. Acad. Nutr. Diet. 2022, 122, 1851–1863. [Google Scholar] [CrossRef] [PubMed]
- Rittenhouse, M.; Scott, J.; Deuster, P. Dietary Supplements: Knowledge and Adverse Event Reporting Practices of Department of Defense Health Care Providers. Mil. Med. 2020, 185, 2076–2081. [Google Scholar] [CrossRef]
- Whaley, D.; Sylvester, J.E.; Deuster, P.A. A Threat to Military Combat Power: Dietary Supplements. Am. J. Med. 2021, 134, 1560–1563. [Google Scholar] [CrossRef]
- Cohen, P.A.; Avula, B.; Katragunta, K.; Khan, I. Recalls, Availability, and Content of Dietary Supplements Following FDA Warning Letters. JAMA 2022, 328, 393–395. [Google Scholar] [CrossRef]
- Cohen, P.A.; Avula, B.; Katragunta, K.; Travis, J.C.; Khan, I. Presence and Quantity of Botanical Ingredients with Purported Performance-Enhancing Properties in Sports Supplements. JAMA Netw. Open 2023, 6, e2323879. [Google Scholar] [CrossRef]
- Cohen, P.A.; Avula, B.; Wang, Y.H.; Zakharevich, I.; Khan, I. Five Unapproved Drugs Found in Cognitive Enhancement Supplements. Neurol. Clin. Pract. 2021, 11, e303–e307. [Google Scholar] [CrossRef]
- Cohen, P.A.; Ellison, R.R.; Travis, J.C.; Gaufberg, S.V.; Gerona, R. Quantity of Phenibut in Dietary Supplements Before and After FDA Warnings. Clin. Toxicol. 2022, 60, 486–488. [Google Scholar] [CrossRef]
- Cohen, P.A.; Travis, J.C.; Vanhee, C.; Ohana, D.; Venhuis, B.J. Nine Prohibited Stimulants Found in Sports and Weight Loss Supplements: Deterenol, Phenpromethamine (Vonedrine), Oxilofrine, Octodrine, Beta-Methylphenylethylamine (BMPEA), 1,3-dimethylamylamine (1,3-DMAA), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylbutylamine (1,3-DMBA) and Higenamine. Clin. Toxicol. 2021, 59, 975–981. [Google Scholar] [CrossRef]
- Cohen, P.A.; Wen, A.; Gerona, R. Prohibited Stimulants in Dietary Supplements After Enforcement Action by the US Food and Drug Administration. JAMA Intern. Med. 2018, 178, 1721–1723. [Google Scholar] [CrossRef] [PubMed]
- Deuster, P.A.; Linderman, J.R.; Hua, D.P.; Lindsey, A.T. Uncovering the World of Dietary Supplements and Performance-Enhancing Substances in the Military. J. Spec. Oper. Med. 2024, 24, 113–119. [Google Scholar] [CrossRef] [PubMed]
- Operation Supplement Safety. DoD Prohibited Dietary Supplements Ingredients List. Available online: https://www.opss.org/dod-prohibited-dietary-supplement-ingredients (accessed on 9 October 2025).
- Food and Drug Administration Office of Inspections and Investigations. Tainted Products Marketed as Dietary Supplements and Foods: Responsibilities of Retailers and Distributors. Available online: https://www.fda.gov/media/186556/download (accessed on 3 October 2025).
- Jędrejko, K.; Catlin, O.; Stewart, T.; Anderson, A.; Muszyńska, B.; Catlin, D.H. Unauthorized Ingredients in “Nootropic” Dietary Supplements: A Review of the History, Pharmacology, Prevalence, International Regulations, and Potential as Doping Agents. Drug Test. Anal. 2023, 15, 803–839. [Google Scholar] [CrossRef] [PubMed]
- Baird, S.; Moran, R.; Hacker, S.; Lawton, D.; Hill, L. Examining the Cost Burden of Dietary Supplements in Older Adults: An Analysis from The AAA Longroad Study. BMC Geriatr. 2025, 25, 177. [Google Scholar] [CrossRef]
- Karnatovskaia, L.V.; Leoni, J.C.; Freeman, M.L. Cardiac Arrest in a 21-Year-Old Man After Ingestion of 1,3-DMAA-Containing Workout Supplement. Clin. J. Sport Med. 2015, 25, e23–e25. [Google Scholar] [CrossRef]
- Operation Supplement Safety. Available online: www.opss.org (accessed on 9 October 2025).
- Crawford, C.; Avula, B.; Lindsey, A.T.; Katragunta, K.; Khan, I.A.; Deuster, P.A. Label Accuracy of Weight Loss Dietary Supplements Marketed Online with Military Discounts. JAMA Netw. Open 2024, 7, e249131. [Google Scholar] [CrossRef]
- Dietary Supplement Health and Education Act of 1994, Public Law 103–417. Available online: https://www.congress.gov/bill/103rd-congress/senate-bill/784 (accessed on 7 October 2025).
- Cohen, P.A.; Avula, B.; Khan, I. The Unapproved Drug Centrophenoxine (Meclofenoxate) in Cognitive Enhancement Dietary Supplements. Clin. Toxicol. 2022, 60, 1156–1158. [Google Scholar] [CrossRef]
- Food and Drug Administration. Health Fraud Notifications. Available online: https://www.fda.gov/drugs/medication-health-fraud/medication-health-fraud-notifications (accessed on 7 October 2025).
- Eichner, A.; Lindsey, A.T.; Coyles, J. Growing Trend of Novel or Experimental Substances Not Approved for Human Use Sold as Consumer Products Poses Threat to Athletes, Service Members, and Public Health. Drug Test. Anal. 2025, 17, 1971–1973. [Google Scholar] [CrossRef]
- Bukhari, A.S.; DiChiara, A.J.; Merrill, E.P.; Wright, A.O.; Cole, R.E.; Hatch-McChesney, A.; McGraw, S.M.; Caldwell, J.A.; Montain, S.J.; Thompson, L.A.; et al. Dietary Supplement Use in US Army Personnel: A Mixed-Methods, Survey and Focus-Group Study Examining Decision Making and Factors Associated with Use. J. Acad. Nutr. Diet. 2021, 121, 1049–1063. [Google Scholar] [CrossRef]
- Currie, T.L.; Crawford, C.C.; Scott, J.M.; Troncoso, M.R.; McCarthy, M.S.; Lindsey, A.T.; Deuster, P.A. Building a Culture of Health Through Leader-Inspired Nutrition. Mil. Med. 2025, 190, 268–272. [Google Scholar] [CrossRef]
- Currie, T.L.; Crawford, C.; Deuster, P.; Lindsey, A.T.; Rittenhouse, M.; Kirkpatrick, K.; Robinson, D.; Troncoso, M.R.; McCarthy, M.S.; Paolicelli, C.; et al. Leader-Inspired Nutrition: A Framework For Promoting Healthy Nutrition Behaviors and a Nutritionally Fulled and Fit Military Force. Nutrients, 2025; under review. [Google Scholar]
- Operation Supplement Safety. Messages for Leadership. Available online: https://www.opss.org/infographic/messages-leadership-handout (accessed on 3 October 2025).
- Eichner, A.K.; Coyles, J.; Fedoruk, M.; Maxey, T.D.; Lenaghan, R.A.; Novitzky, J.; Lindsey, A.T.; Deuster, P.A. Essential Features of Third-Party Certification Programs for Dietary Supplements: A Consensus Statement. Curr. Sports Med. Rep. 2019, 18, 178–182. [Google Scholar] [CrossRef]
- Jones, D.R.; Kasper, K.B.; Deuster, P.A. Third-Party Evaluation: A Review of Dietary Supplements Dispensed by Military Treatment Facilities From 2007 to 2011. Mil. Med. 2015, 180, 737–741. [Google Scholar] [CrossRef] [PubMed]
- Pyle, S.A.; Haddock, C.K.; Poston, W.S.; Bray, R.M.; Williams, J. Tobacco Use and Perceived Financial Strain Among Junior Enlisted in the U.S. Military in 2002. Prev. Med. 2007, 45, 460–463. [Google Scholar] [CrossRef]
- OPSS Scorecard: Check your Dietary Supplement. Available online: https://www.opss.org/opss-scorecard (accessed on 2 June 2025).
- Operation Supplement Safety. Ask the Expert. Available online: https://www.opss.org/ask-the-expert (accessed on 2 June 2025).
- Ainsworth, N.P.; Thrower, S.N.; Petróczi, A. Two Sides of the Same Coin: A Qualitative Exploration of Experiential and Perceptual Factors Which Influence the Clinical Interaction Between Physicians and Anabolic-Androgenic Steroid Using Patients in the UK. Emerg. Trends Drugs Addict. Health 2022, 2, 100033. [Google Scholar] [CrossRef]
- Holubeck, P.A.; Eksi, A.C.; Gillett, K.; O’Hara, J.; McGoldrick, D.J.; Brown, D.R.; McCarthy, A.D. Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations. Cureus 2024, 16, e52011. [Google Scholar] [CrossRef] [PubMed]
- Mallick, M.; Camacho, C.B.; Daher, J.; El Khoury, D. Dietary Supplements: A Gateway to Doping? Nutrients 2023, 15, 881. [Google Scholar] [CrossRef]
- Pope, H.G., Jr.; Wood, R.I.; Rogol, A.; Nyberg, F.; Bowers, L.; Bhasin, S. Adverse health consequences of performance-enhancing drugs: An Endocrine Society scientific statement. Endocr. Rev. 2014, 35, 341–375. [Google Scholar] [CrossRef]

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Lindsey, A.T.; Crawford, C.; Currie, T.L.; McCarthy, M.; Deuster, P.A. Leader-Inspired Nutrition: Promoting Safe Dietary Supplement Use for Service Members. Nutrients 2025, 17, 3592. https://doi.org/10.3390/nu17223592
Lindsey AT, Crawford C, Currie TL, McCarthy M, Deuster PA. Leader-Inspired Nutrition: Promoting Safe Dietary Supplement Use for Service Members. Nutrients. 2025; 17(22):3592. https://doi.org/10.3390/nu17223592
Chicago/Turabian StyleLindsey, Andrea T., Cindy Crawford, Tanisha L. Currie, Mary McCarthy, and Patricia A. Deuster. 2025. "Leader-Inspired Nutrition: Promoting Safe Dietary Supplement Use for Service Members" Nutrients 17, no. 22: 3592. https://doi.org/10.3390/nu17223592
APA StyleLindsey, A. T., Crawford, C., Currie, T. L., McCarthy, M., & Deuster, P. A. (2025). Leader-Inspired Nutrition: Promoting Safe Dietary Supplement Use for Service Members. Nutrients, 17(22), 3592. https://doi.org/10.3390/nu17223592

