Fecal Calprotectin Determination in a Cohort of Children with Cow’s Milk Allergy
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.1.1. Fecal Calprotectin Measurement
2.1.2. Ethics
2.1.3. Informed Consent Statement
2.1.4. Statistical Analysis
3. Results
Patients’ Characteristics
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Patients’ Characteristics | (n = 51) |
---|---|
Boys/girls | 34/17 (67/33%) |
Age (years) | 1.3 [0.7, 2.2] |
Weight (kg) | 10.5 [8.8, 12.8] |
Height (cm) | 78.0 [73.5, 90.5] |
Breastfed/formula fed/mixed feeding | 25/15/11 (49/30/21%) |
IgE-mediated/non-IgE-mediated CMA | 25/26 (49/51%) |
Tot IgE > 15/<15 (kU/L) | 22/28 (56/44%) |
sIgE to CM > 0.35/<0.35 kU/L | 29/21 (58/42%) |
sIgE to α-lactalbumin > 0.35/<0.35 kU/L | 13/37 (74/26%) |
sIgE to β-lactoglobulin > 0.35/<0.35 kU/L | 18/55 (25/75%) |
sIgE to casein > 0.35/<0.35 kU/L | 14/36 (28/72%) |
Symptoms | |
Vomiting | 20 (44%) |
Diarrhea/Constipation | 37 (73%) |
Abdominal pain | 21 (41%) |
Skin involvement (urticaria, dermatitis) | 38 (75%) |
Measurements | |
Calprotectin T1 (mg/kg) | 30 [15.5, 63.9] |
Calprotectin T2 (mg/kg) | 16.1 [10.0, 30.0] |
CoMiSS T1 | 8.5 [6.0, 13.0] |
CoMiSS T2 | 3.0 [2.0, 5.0] |
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Anania, C.; Mondì, F.; Brindisi, G.; Spagnoli, A.; De Canditiis, D.; Gesmini, A.; Marchetti, L.; Fichera, A.; Piccioni, M.G.; Zicari, A.M.; et al. Fecal Calprotectin Determination in a Cohort of Children with Cow’s Milk Allergy. Nutrients 2025, 17, 194. https://doi.org/10.3390/nu17010194
Anania C, Mondì F, Brindisi G, Spagnoli A, De Canditiis D, Gesmini A, Marchetti L, Fichera A, Piccioni MG, Zicari AM, et al. Fecal Calprotectin Determination in a Cohort of Children with Cow’s Milk Allergy. Nutrients. 2025; 17(1):194. https://doi.org/10.3390/nu17010194
Chicago/Turabian StyleAnania, Caterina, Filippo Mondì, Giulia Brindisi, Alessandra Spagnoli, Daniela De Canditiis, Arianna Gesmini, Lavinia Marchetti, Alessia Fichera, Maria Grazia Piccioni, Anna Maria Zicari, and et al. 2025. "Fecal Calprotectin Determination in a Cohort of Children with Cow’s Milk Allergy" Nutrients 17, no. 1: 194. https://doi.org/10.3390/nu17010194
APA StyleAnania, C., Mondì, F., Brindisi, G., Spagnoli, A., De Canditiis, D., Gesmini, A., Marchetti, L., Fichera, A., Piccioni, M. G., Zicari, A. M., & Olivero, F. (2025). Fecal Calprotectin Determination in a Cohort of Children with Cow’s Milk Allergy. Nutrients, 17(1), 194. https://doi.org/10.3390/nu17010194