Biomedical Indicators of Patients with Non-Puerperal Mastitis: A Retrospective Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patients and Data Collection
2.2. Pathological Diagnosis
2.3. Statistical Analysis
3. Results
3.1. Baseline Characteristics and Biomedical Indicators of NPM and Benign Breast Mass Patients
3.2. Baseline Characteristics, Clinical and Ultrasound Features, and Treatment of Non-Puerperal Mastitis Patients
3.3. Univariate and Multivariate Logistic Analysis for Risks between Non-Puerperal Mastitis and Benign Breast Mass
3.4. Biomedical Indicators of MDE and GLM Patients
3.5. Pathological Characteristics of Non-Puerperal Mastitis
4. Discussions
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Variable | Non-Puerperal Mastitis (284) | Benign Breast Mass (1128) | p-Value |
---|---|---|---|
ALT (U/L) M (25%, 75%) | 13.7 (11.8, 18.8) | 15.6 (12.0, 21.4) | 0.366 |
AST (U/L) M (25%, 75%) | 18.9 (15.1, 24.0) | 19.6 (16.2, 23.6) | 0.36 |
GGT (U/L) M (25%, 75%) | 19.8 (15.0, 25.1) | 14.9 (11.3, 21.6) | 0.455 |
LDH (U/L) M (25%, 75%) | 174 (158, 198) | 168 (149,189) | 0.156 |
CK (U/L) M (25%, 75%) | 62.6 (52.0, 80.0) | 69.0 (53.6, 91.2) | 0.355 |
TC (mmol/L) M (25%, 75%) | 4.5 (4.1, 4.9) | 4.46 (3.85, 5.07) | 0.964 |
TG (mmol/L) M (25%, 75%) | 1.15 (0.78, 1.62) | 0.94 (0.70, 1.35) | 0.081 |
HDL-C (mmol/L) M (25%, 75%) | 1.25 (1.08, 1.44) | 1.4 (1.2, 1.6) | 0.002 |
LDL-C (mmol/L) M (25%, 75%) | 2.81 (2.50, 3.20) | 2.65 (2.18, 3.21) | 0.287 |
Lp(a) (mg/L) M (25%, 75%) | 159 (59, 398) | 125 (59, 246) | 0.022 |
GLU (mmol/L) M (25%, 75%) | 5.18 (4.85, 5.46) | 4.93 (4.60, 5.39) | 0.023 |
Urea (mmol/L) M (25%, 75%) | 4.0 (3.6, 4.9) | 4.6 (3.8, 5.5) | 0.009 |
Cr (μmol/L) M (25%, 75%) | 50.4 (46.3, 57.1) | 55.0 (46.0, 62.0) | 0.002 |
Variable | Non-Puerperal Mastitis (284) | Benign Breast Mass (1128) | OR | p-Value | 95% CI |
---|---|---|---|---|---|
Age (years) | 35.6 ± 9.8 | 44.3 ± 12.3 | 1.073 | <0.001 | 1.059–1.088 |
High blood pressure | 2.221 | 0.003 | 1.318–3.741 | ||
Yes | 17 | 39 | |||
No | 267 | 1082 | |||
AST (U/L) M (25%, 75%) | 18.9 (15.1, 24.0) | 19.6 (16.2, 23.6) | 0.991 | 0.36 | 0.971–1.011 |
GGT (U/L) M (25%, 75%) | 19.8 (15.0, 25.1) | 14.9 (11.3, 21.6) | 0.999 | 0.455 | 0.996–1.002 |
LDH (U/L) M (25%, 75%) | 174 (158, 198) | 168 (149, 189) | 0.997 | 0.156 | 0.992–1.001 |
CK (U/L) M (25%, 75%) | 62.6 (52, 80) | 69 (53.6, 91.2) | 1.004 | 0.355 | 0.996–1.012 |
TC (mmol/L) M (25%, 75%) | 4.5 (4.1, 4.9) | 4.46 (3.85, 5.07) | 1.007 | 0.964 | 0.754–1.343 |
TG (mmol/L) M (25%, 75%) | 1.15 (0.78, 1.62) | 0.94 (0.70, 1.35) | 0.761 | 0.081 | 0.560–1.034 |
HDL-C (mmol/L) (25%, 75%) | 1.25 (1.08, 1.44) | 1.4 (1.2, 1.6) | 4.514 | 0.002 | 1.735–11.746 |
LDL-C (mmol/L) M (25%, 75%) | 2.81 (2.5, 3.2) | 2.65 (2.18, 3.21) | 0.837 | 0.287 | 0.603–1.161 |
Lp(a) (mg/L) M (25%, 75%) | 159 (59, 398) | 125 (59, 246) | 0.999 | 0.022 | 0.998–1.000 |
GLU (mmol/L) M (25%, 75%) | 5.18 (4.85, 5.46) | 4.93 (4.6, 5.39) | 0.845 | 0.023 | 0.732–0.977 |
Urea (mmol/L) M (25%, 75%) | 4.0 (3.6, 4.9) | 4.6 (3.8, 5.5) | 1.375 | 0.009 | 1.081–1.748 |
Cr (μmol/L) M (25%, 75%) | 50.4 (46.3, 57.1) | 55 (46, 62) | 1.051 | 0.002 | 1.019–1.084 |
Variable | Non-Puerperal Mastitis (284) | Benign Breast Mass (1128) | OR | p-Value | 95% CI |
---|---|---|---|---|---|
Age (years) | 35.6 ± 9.8 | 44.3 ± 12.3 | 1.065 | 0.003 | 1.021–1.110 |
High blood pressure | 6.036 | 0.108 | 0.674–54.081 | ||
Yes | 17 | 39 | |||
No | 267 | 1082 | |||
HDL-C (mmol/L) M (25%, 75%) | 1.25 (1.08, 1.44) | 1.4 (1.2, 1.6) | 4.386 | 0.025 | 1.206–15.946 |
Lp(a) (mg/L) M (25%, 75%) | 159 (59, 398) | 125 (59, 246) | 0.998 | 0.021 | 0.997–1.000 |
GLU (mmol/L) M (25%, 75%) | 5.18 (4.85, 5.46) | 4.93 (4.6, 5.39) | 0.567 | 0.008 | 0.373–0.862 |
Urea (mmol/L) M (25%, 75%) | 4.0 (3.6, 4.9) | 4.6 (3.8, 5.5) | 1.159 | 0.37 | 0.840–1.600 |
Cr (μmol/L) M (25%, 75%) | 50.4 (46.3, 57.1) | 55 (46, 62) | 1.037 | 0.081 | 0.995–1.080 |
Variable | Mammary Duct Ectasia (150) | Granulomatous Mastitis (38) | p-Value |
---|---|---|---|
AST (U/L) M (25%, 75%) | 18.5 (14.8, 23.4) | 19.8 (15.6, 48.9) | 0.5177 |
ALP (U/L) M (25%, 75%) | 74.3 (59.4, 91.0) | 68.0 (57.0, 88.0) | 0.6894 |
GGT (U/L) M (25%, 75%) | 19.7 (14.1, 27.7) | 17.7 (14.1, 28.8) | 0.9848 |
LDH (U/L) M (25%, 75%) | 174.5 (159.5, 204.5) | 156.5 (141.0, 168.0) | 0.03 |
CK (U/L) M (25%, 75%) | 77.0 (52.5, 87.9) | 53.5 (40.5, 63.5) | 0.0346 |
TC (mmol/L) M (25%, 75%) | 4.7 (4.5, 5.4) | 4.1 (3.6, 4.5) | 0.0102 |
TG (mmol/L) M (25%, 75%) | 0.93 (0.68, 1.61) | 1.30 (0.90, 1.77) | 0.4242 |
HDL-C (mmol/L) M (25%, 75%) | 1.36 (1.15, 1.64) | 1.07 (1.04, 1.15) | 0.0026 |
LDL-C (mmol/L) M (25%, 75%) | 0.93 (2.62, 3.44) | 2.64 (2.11, 2.91) | 0.0355 |
Lp(a) (mg/L) M (25%, 75%) | 246 (96, 456) | 111 (48, 159) | 0.0771 |
GLU (mmol/L) M (25%, 75%) | 5.23 (4.87, 5.43) | 4.92 (4.66, 5.66) | 0.7533 |
Urea (mmol/L) M (25%, 75%) | 4.0 (3.5, 4.9) | 3.8 (3.4, 4.3) | 0.4436 |
Cr (μmol/L) M (25%, 75%) | 49.4 (46.2, 57.6) | 43.6 (42.2, 50.4) | 0.0648 |
Variable | Mammary Duct Ectasia (150) | Granulomatous Mastitis (38) | p-Value |
---|---|---|---|
Duct and lobular | <0.001 | ||
No | 76 | 6 | |
Duct | 46 | 4 | |
Lobular | 7 | 17 | |
Duct and lobular | 21 | 11 | |
Plasma cell | <0.001 | ||
Yes | 146 | 24 | |
No | 4 | 14 | |
Lymphocyte | |||
Yes | 137 | 23 | <0.001 |
No | 13 | 15 | |
Neutrophil | |||
Yes | 122 | 21 | 0.002 |
No | 28 | 17 | |
Eosinophil | 1.00 | ||
Yes | 1 | 0 | |
No | 149 | 38 | |
Histocyte response | <0.001 | ||
Yes | 66 | 5 | |
No | 84 | 33 | |
Multicenter giant cell response | 0.579 | ||
Yes | 60 | 13 | |
No | 90 | 25 | |
Granulomatous inflammation | <0.001 | ||
Yes | 74 | 32 | |
No | 76 | 6 |
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Shi, L.; Wu, J.; Hu, Y.; Zhang, X.; Li, Z.; Xi, P.-W.; Wei, J.-F.; Ding, Q. Biomedical Indicators of Patients with Non-Puerperal Mastitis: A Retrospective Study. Nutrients 2022, 14, 4816. https://doi.org/10.3390/nu14224816
Shi L, Wu J, Hu Y, Zhang X, Li Z, Xi P-W, Wei J-F, Ding Q. Biomedical Indicators of Patients with Non-Puerperal Mastitis: A Retrospective Study. Nutrients. 2022; 14(22):4816. https://doi.org/10.3390/nu14224816
Chicago/Turabian StyleShi, Liang, Jing Wu, Yue Hu, Xu Zhang, Zhi Li, Pei-Wen Xi, Ji-Fu Wei, and Qiang Ding. 2022. "Biomedical Indicators of Patients with Non-Puerperal Mastitis: A Retrospective Study" Nutrients 14, no. 22: 4816. https://doi.org/10.3390/nu14224816