Next Article in Journal
Impact of COVID-19 Lockdown in Eating Disorders: A Multicentre Collaborative International Study
Previous Article in Journal
Adolescent Self-Efficacy for Diet and Exercise Following a School-Based Multicomponent Lifestyle Intervention
 
 
Article

Jasmine Tea Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-like Behavior in Rats via the Gut-Brain Axis

1
Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, China
2
National Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, China
3
Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, China
*
Author to whom correspondence should be addressed.
Academic Editor: Panteleimon Giannakopoulos
Nutrients 2022, 14(1), 99; https://doi.org/10.3390/nu14010099
Received: 29 November 2021 / Revised: 22 December 2021 / Accepted: 23 December 2021 / Published: 27 December 2021
(This article belongs to the Section Nutrition and Public Health)
The number of depressed people has increased worldwide. Dysfunction of the gut microbiota has been closely related to depression. The mechanism by which jasmine tea ameliorates depression via the brain-gut-microbiome (BGM) axis remains unclear. Here, the effects of jasmine tea on rats with depressive-like symptoms via the gut microbiome were investigated. We first established a chronic unpredictable mild stress (CUMS) rat model to induce depressive symptoms and measured the changes in depression-related indicators. Simultaneously, the changes in gut microbiota were investigated by 16S rRNA sequencing. Jasmine tea treatment improved depressive-like behaviors and neurotransmitters in CUMS rats. Jasmine tea increased the gut microbiota diversity and richness of depressed rats induced by CUMS. Spearman’s analysis showed correlations between the differential microbiota (Patescibacteria, Firmicutes, Bacteroidetes, Spirochaetes, Elusimicrobia, and Proteobacteria) and depressive-related indicators (BDNF, GLP-1, and 5-HT in the hippocampus and cerebral cortex). Combined with the correlation analysis of gut microbiota, the result indicated that jasmine tea could attenuate depression in rats via the brain- gut-microbiome axis. View Full-Text
Keywords: jasmine tea; CUMS; depression-like behaviors; neurotransmitters; gut microbiota jasmine tea; CUMS; depression-like behaviors; neurotransmitters; gut microbiota
Show Figures

Figure 1

MDPI and ACS Style

Zhang, Y.; Huang, J.; Xiong, Y.; Zhang, X.; Lin, Y.; Liu, Z. Jasmine Tea Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-like Behavior in Rats via the Gut-Brain Axis. Nutrients 2022, 14, 99. https://doi.org/10.3390/nu14010099

AMA Style

Zhang Y, Huang J, Xiong Y, Zhang X, Lin Y, Liu Z. Jasmine Tea Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-like Behavior in Rats via the Gut-Brain Axis. Nutrients. 2022; 14(1):99. https://doi.org/10.3390/nu14010099

Chicago/Turabian Style

Zhang, Yangbo, Jianan Huang, Yifan Xiong, Xiangna Zhang, Yong Lin, and Zhonghua Liu. 2022. "Jasmine Tea Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-like Behavior in Rats via the Gut-Brain Axis" Nutrients 14, no. 1: 99. https://doi.org/10.3390/nu14010099

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop