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Article

Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation

1
Servicio de Reumatología, Hospital Universitario de Canarias, 38320 La Laguna, Spain
2
Servicio de Análisis Clínicos, Hospital Universitario de Canarias, 38320 La Laguna, Spain
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Departamento de Estadística e Investigación Operativa, Universidad de La Laguna, 38320 La Laguna, Spain
4
Departamento de Medicina Interna, Dermatología y Psiquiatría, Universidad de La Laguna, 38320 La Laguna, Spain
*
Author to whom correspondence should be addressed.
Academic Editors: Alejandro Cifuentes and Alberto Valdés
Nutrients 2021, 13(5), 1647; https://doi.org/10.3390/nu13051647
Received: 7 April 2021 / Revised: 8 May 2021 / Accepted: 10 May 2021 / Published: 13 May 2021
(This article belongs to the Special Issue Food and Nutrition Research – the Omics Era)
The use of vitamin D (VitD) supplements has become widespread in the last decade due not only to the dissociation between the blood levels recommended as “optimal” and those shown by the healthy population but also to its presumed beneficial effects on multiple disorders. This work evaluated the levels of 25-hydroxyvitamin D (25(OH)D) in a healthy population of European origin living in a region with high solar irradiation. In serum samples from a population-based study conducted in the Canary Islands, levels of 25(OH)D were analyzed. In 876 individuals who had no history of kidney or malabsorption disorders and, who had not been treated with calcium and/or VitD supplementation, the median 25(OH)D level was 26.3 (5th; 95th percentile, 14.3; 45.8) ng/mL. Notably, 65.4% of the population had 25(OH)D blood levels below 30 ng/mL, 23.4% below 20 ng/mL and 6.4% below 15 ng/mL. Based on the lack of evidence supporting causality between 25(OH)D levels below what is recommended as optimal (≥20 ng/mL, or even ≥30 ng/mL) and major skeletal and non-skeletal diseases, and in light of the distribution of the concentration of this vitamin in healthy adults living under optimal conditions of solar irradiation, it seems reasonable to consider 25(OH)D levels below 20 ng/mL and close to 15 ng/mL as adequate for the general population. View Full-Text
Keywords: vitamin D levels; population-based distribution; healthy adults; high solar irradiation vitamin D levels; population-based distribution; healthy adults; high solar irradiation
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MDPI and ACS Style

García-Dorta, A.; Medina-Vega, L.; Villacampa-Jiménez, J.J.; Hernández-Díaz, M.; Bustabad-Reyes, S.; González-Dávila, E.; Díaz-González, F. Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation. Nutrients 2021, 13, 1647. https://doi.org/10.3390/nu13051647

AMA Style

García-Dorta A, Medina-Vega L, Villacampa-Jiménez JJ, Hernández-Díaz M, Bustabad-Reyes S, González-Dávila E, Díaz-González F. Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation. Nutrients. 2021; 13(5):1647. https://doi.org/10.3390/nu13051647

Chicago/Turabian Style

García-Dorta, Alicia, Lillian Medina-Vega, Jacobo J. Villacampa-Jiménez, Marta Hernández-Díaz, Sagrario Bustabad-Reyes, Enrique González-Dávila, and Federico Díaz-González. 2021. "Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation" Nutrients 13, no. 5: 1647. https://doi.org/10.3390/nu13051647

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