Vitamin D Serum Levels in Subjects Tested for SARS-CoV-2: What Are the Differences among Acute, Healed, and Negative COVID-19 Patients? A Multicenter Real-Practice Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Data Collection
2.2. Study Participants
2.3. Experimental Protocol
2.4. Endpoints
2.5. Reverse Transcription Polymerase Chain Reaction (RT-PCR) Assay for SARS-CoV-2
2.6. Serum 25(OH)D3 and Interleukin-6 (IL-6) Detection
2.7. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Appendix A
References
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Sex | Age (years) | 25 (OH)D3 (ng/mL) | IL-6 (pg/mL) |
---|---|---|---|
Female | 62 | 0.35 | 2.1 |
Female | 63 | 0.25 | 2.6 |
Female | 57 | 0.30 | 2.5 |
Female | 60 | 0.72 | 2.8 |
Male | 74 | 0.84 | 4.7 |
Male | 69 | 0.90 | 4.3 |
Sex | Age (Years) | 25 (OH)D3 (ng/mL) | IL-6 (pg/mL) | ||||
---|---|---|---|---|---|---|---|
Admission | After 2 Weeks | p-Value | Admission | After 2 Weeks | p-Value | ||
F | 73 | 15 | 13 | 132.1 | 2 | ||
F | 74 | 14 | 12 | 151.8 | 1.5 | ||
F | 73 | 13 | 11 | 111 | 1.8 | ||
F | 80 | 12 | 11 | 99 | 0.9 | ||
F | 74 | 14 | 13 | 144.3 | 3 | ||
M | 76 | 19 | 18 | 0.025 | 141 | 2 | 0.0022 |
M | 82 | 12 | 11 | 200 | 3.5 | ||
M | 80 | 12 | 12 | 89 | 4.2 | ||
M | 81 | 13 | 13 | 65 | 3 | ||
M | 78 | 12 | 11 | 185 | 2.1 | ||
M | 77 | 18 | 17 | 162 | 2 | ||
M | 79 | 19 | 18 | 133 | 1.8 |
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Gallelli, L.; Mannino, G.C.; Luciani, F.; de Sire, A.; Mancuso, E.; Gangemi, P.; Cosco, L.; Monea, G.; Averta, C.; Minchella, P.; et al. Vitamin D Serum Levels in Subjects Tested for SARS-CoV-2: What Are the Differences among Acute, Healed, and Negative COVID-19 Patients? A Multicenter Real-Practice Study. Nutrients 2021, 13, 3932. https://doi.org/10.3390/nu13113932
Gallelli L, Mannino GC, Luciani F, de Sire A, Mancuso E, Gangemi P, Cosco L, Monea G, Averta C, Minchella P, et al. Vitamin D Serum Levels in Subjects Tested for SARS-CoV-2: What Are the Differences among Acute, Healed, and Negative COVID-19 Patients? A Multicenter Real-Practice Study. Nutrients. 2021; 13(11):3932. https://doi.org/10.3390/nu13113932
Chicago/Turabian StyleGallelli, Luca, Gaia Chiara Mannino, Filippo Luciani, Alessandro de Sire, Elettra Mancuso, Pietro Gangemi, Lucio Cosco, Giuseppe Monea, Carolina Averta, Pasquale Minchella, and et al. 2021. "Vitamin D Serum Levels in Subjects Tested for SARS-CoV-2: What Are the Differences among Acute, Healed, and Negative COVID-19 Patients? A Multicenter Real-Practice Study" Nutrients 13, no. 11: 3932. https://doi.org/10.3390/nu13113932