Next Article in Journal
The Neuropathology of Gluten-Related Neurological Disorders: A Systematic Review
Previous Article in Journal
Gut Microbiota Dysbiosis in Patients with Biopsy-Proven Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study in Taiwan
Open AccessArticle

Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial

1
Department of Surgery, Odontostomatology and Maternal Sciences, Fibromyalgia Diagnosis and Treatment Centre, University of Verona, 37134 Verona, Italy
2
Department of Surgery and Oncology, General and Pancreatic Surgery, Pancreas Institute, University of Verona Hospital Trust, 37134 Verona, Italy
3
Department of Medicine, Regional Specialized Centre for Biomolecular and Histomorphometric Research on Skeletal and Degenerative Diseases, University of Verona, 37134 Verona, Italy
4
Department of Neurosciences, Biomedicine and Movement Sciences, Neuromotor and Cognitive Rehabilitation Research Sciences, University of Verona, 37134 Verona, Italy
*
Authors to whom correspondence should be addressed.
Nutrients 2020, 12(3), 821; https://doi.org/10.3390/nu12030821
Received: 20 February 2020 / Revised: 12 March 2020 / Accepted: 13 March 2020 / Published: 19 March 2020
(This article belongs to the Section Nutrition and Public Health)
Objectives: Fibromyalgia syndrome (FMS) is a chronic clinical condition characterized by pain, fatigue, altered sleep, and cognitive disturbances. The purpose of this study was to compare two alternative treatments (nutraceutical and acupuncture) in FMS patients through a randomized clinical trial. Research Methods: A total of 60 FMS female patients were randomized for treatment with a nutritional combination containing coenzyme Q10, vitamin D, alpha-lipoic acid, magnesium, and tryptophan (Migratens® Group) or acupuncture treatment (Acupuncture Group) performed according the principles of traditional Chinese medicine (TCM), both for 3 months. Changes in pain and in quality of life (QoL) measured with a Fibromyalgia Impact Questionnaire Score-Revised (FIQ-R) and the Fibromyalgia Severity Scale (FSS) were performed at 1, 3, and 6 months after the start of treatments. Results: A total of 55 patient completed the study (21 in the Migratens® Group and 34 in the Acupuncture Group). Migratens® treatment shows a statistically significant reduction of pain 1 month after the start of therapy (T1, p = 0.025), strengthened after 3 months with maintenance of treatment (p = 0.012). The efficacy in reducing pain was apparent in the Acupuncture Group at all post-treatment determinations and at follow-up (T1 and T2 p = <0.001). Regarding QoL, improvement in FIQ-R and FSS values was revealed in both groups. Conclusion: The nutraceutical approach with Migratens® seems to be an effective option to for patients with FMS. Our experience confirmed also the validity of acupuncture in these patients. Considering the complexity of the management of FMS patients, our results suggest a cyclical and sequential, or even concurrent treatment with different approaches, to improve the efficacy and the compliance of patients to long-term treatment View Full-Text
Keywords: acupuncture; fibromyalgia; nutraceutical; dietary supplementation; quality of life; pain acupuncture; fibromyalgia; nutraceutical; dietary supplementation; quality of life; pain
Show Figures

Figure 1

MDPI and ACS Style

Vittorio, S.; Erica, S.; Cinzia, C.; Alvise, M.; Elena, M.; Alessandro, P.; Enrico, P.; Katia, D.; Teresa, V.M.; Luca, D.C. Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial. Nutrients 2020, 12, 821.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop