Effects of Dietary Vitamin B6 Restriction on Hepatic Gene Expression Profile of Non-Obese and Obese Mice
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals and Diets
2.2. Serum and Hepatic Biochemical Analysis
2.3. Tissue Histologic Examination
2.4. Microarray Analysis
2.5. Statistical Analysis
3. Results
3.1. Effects of Dietary Vitamin B6 Restriction on Serum and Hepatic Biochemical Parameters of Mice
3.2. Effects of Dietary Vitamin B6 Restriction on Hepatic Transcriptome of Mice
3.3. Effects of Dietary Vitamin B6 Restriction on Hepatic Transcriptome of Mice Fed a Low-Fat Diet
3.4. Effects of Dietary Vitamin B6 Restriction on Hepatic Transcriptome of Mice Fed a High-Fat Diet
3.5. Effects of High-Fat Diet on Hepatic Vitamin B6 Metabolism and Function
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Um, H.-J.; Ko, J.W.; Won, S.B.; Kwon, Y.H. Effects of Dietary Vitamin B6 Restriction on Hepatic Gene Expression Profile of Non-Obese and Obese Mice. Nutrients 2020, 12, 3821. https://doi.org/10.3390/nu12123821
Um H-J, Ko JW, Won SB, Kwon YH. Effects of Dietary Vitamin B6 Restriction on Hepatic Gene Expression Profile of Non-Obese and Obese Mice. Nutrients. 2020; 12(12):3821. https://doi.org/10.3390/nu12123821
Chicago/Turabian StyleUm, Hyun-Jee, Je Won Ko, Sae Bom Won, and Young Hye Kwon. 2020. "Effects of Dietary Vitamin B6 Restriction on Hepatic Gene Expression Profile of Non-Obese and Obese Mice" Nutrients 12, no. 12: 3821. https://doi.org/10.3390/nu12123821