Next Article in Journal
Antitumor Effects of Quercetin in Hepatocarcinoma In Vitro and In Vivo Models: A Systematic Review
Previous Article in Journal
Food Advertising and Prevention of Childhood Obesity in Spain: Analysis of the Nutritional Value of the Products and Discursive Strategies Used in the Ads Most Viewed by Children from 2016 to 2018
Open AccessArticle

Decreased Bioimpedance Phase Angle in Patients with Diabetic Chronic Kidney Disease Stage 5

Department of Nephrology, Yonsei University Wonju College of Medicine, Wonju, Kang-won 26426, Korea
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(12), 2874; https://doi.org/10.3390/nu11122874
Received: 16 October 2019 / Revised: 18 November 2019 / Accepted: 22 November 2019 / Published: 25 November 2019
Early detection and regular monitoring of the nutritional status of patients with diabetic chronic kidney disease (DMCKD) with reliable tools are necessary. We aimed to determine the clinical significance of the phase angle (PhA) in patients with DMCKD stage 5 not undergoing dialysis. A total of 219 patients (non-diabetic CKD stage 5 [nDMCKD5], n = 84; diabetic CKD stage 5 [DMCKD5], n = 135) were analyzed. The nDMCKD5 group had a significantly higher PhA (p = 0.001), intracellular water/body weight (p = 0.001), and albumin level (p = 0.010) than the DMCKD5 group. The DMCKD5 group experienced significantly more overhydration (p < 0.001). The PhA was positively associated with the lean tissue index (LTI) (r = 0.332; p < 0.001), hemoglobin level (r = 0.223; p = 0.010), albumin level (r = 0.524; p < 0.001), and estimated glomerular filtration rate (eGFR; r = 0.204; p = 0.018) in the DMCKD5 group. Multivariate logistic regression analysis showed the eGFR (odds ratio [OR]: 0.824, 95% confidence interval [CI]: 0.698–0.974); p = 0.023), LTI (OR: 0.771, 95% CI: 0.642–0.926; p = 0.005), and albumin level (OR: 0.131, 95% CI: 0.051–0.338; p < 0.001) were significantly associated with undernutrition (PhA < 4.17°) in the DMCKD5 group. Our observations suggest that the PhA could be used as a marker to reflect the nutritional status in patients with DMCKD5. View Full-Text
Keywords: albumin; chronic kidney disease; diabetes type 2; impedance; inflammation; nutrition albumin; chronic kidney disease; diabetes type 2; impedance; inflammation; nutrition
MDPI and ACS Style

Han, B.-G.; Lee, J.Y.; Kim, J.-S.; Yang, J.-W. Decreased Bioimpedance Phase Angle in Patients with Diabetic Chronic Kidney Disease Stage 5. Nutrients 2019, 11, 2874.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop