Anti-Fatigue Effects of Yogurt Fermented with Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1 in Healthy People Suffering from Summer Heat Fatigue: A Randomized, Double-Blind, Placebo-Controlled Trial
by
Seiya Makino 1,*, Jun Hemmi 1, Hiroshi Kano 1, Mari Kashiwagi 2, Kenichi Hojo 2 and Yukio Asami 1
Seiya Makino 1,*, Jun Hemmi 1, Hiroshi Kano 1, Mari Kashiwagi 2, Kenichi Hojo 2 and Yukio Asami 1
1
Food Microbiology Research Laboratories, R&D Division, Meiji Co., Ltd., 1-29-1 Nanakuni, Hachiouji, Tokyo 192-0919, Japan
2
Food Development Laboratories, R&D Division, Meiji Co., Ltd, 1-29-1 Nanakuni, Hachiouji, Tokyo 192-0919, Japan
*
Author to whom correspondence should be addressed.
Nutrients 2018, 10(7), 798; https://doi.org/10.3390/nu10070798
Received: 25 April 2018 / Revised: 6 June 2018 / Accepted: 19 June 2018 / Published: 21 June 2018
Fatigue caused by summer heat is a typical indefinite complaint along with anorexia, loss of sleep, stress, lack of motivation and, in some cases, catching a cold. Yogurt fermented with Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1 has been shown to stimulate the immune system and reduce the risk of catching colds. Here, we conducted a randomized, double-blinded, placebo-controlled trial to investigate whether ingesting this yogurt could ameliorate summer heat fatigue in 49 healthy males (median age 40.0 ± 6.0 years; 30–49 years) who felt fatigued every summer. Fatigue was evaluated by visual analogue scales (VAS) and the balance of sympathetic/parasympathetic nervous systems. After 12 weeks of ingestion in early autumn, the VAS fatigue scores in the yogurt group were lower than those of the placebo group. These results indicate that yogurt fermented with L. bulgaricus OLL1073R-1 can ameliorate summer heat fatigue lasting up to early autumn.
View Full-Text
Keywords:
anti-fatigue; yogurt; summer heat; stress
▼
Show Figures
Figure 1
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Makino, S.; Hemmi, J.; Kano, H.; Kashiwagi, M.; Hojo, K.; Asami, Y. Anti-Fatigue Effects of Yogurt Fermented with Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1 in Healthy People Suffering from Summer Heat Fatigue: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients 2018, 10, 798.
Show more citation formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
