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Clinics and Practice
Volume 7
Issue 2
10.4081/cp.2017.943
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Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Brief Report

Etiology and Laboratory Abnormalities in Bacterial Meningitis in Neonates and Young Infants

by
David Kotzbauer
*,
Curtis Travers
,
Craig Shapiro
,
Margaux Charbonnet
,
Anthony Cooley
,
Deborah Andresen
and
Gary Frank
Department of Pediatrics, Children’s Healthcare of Atlanta, Atlanta, GA, USA
*
Author to whom correspondence should be addressed.
Clin. Pract. 2017, 7(2), 943; https://doi.org/10.4081/cp.2017.943
Submission received: 23 January 2017 / Revised: 2 March 2017 / Accepted: 17 March 2017 / Published: 21 April 2017

Abstract

We conducted a retrospective review of electronic medical records of all cases of bacterial meningitis in neonates and young infants at our institution from 2004 to 2014. Fifty-six cases were identified. The most common causative organism was group B streptococcus, followed by Escherichia coli and then Listeria monocytogenes. Fortyfour of the 56 patients in the study had abnormalities of the blood white blood cell (WBC) count. The most common WBC count abnormalities were leukopenia and elevation of the immature to total (I:T) neutrophil ratio. Six patients in the case series lacked cerebrospinal fluid (CSF) pleocytosis. Overall, just 3 of the 56 patients had normal WBC count with differential, CSF WBC count, and urinalysis. Only 1 of the 56 patients was well appearing with all normal lab studies. Our study indicates that bacterial meningitis may occur without CSF pleocytosis but very infrequently occurs with all normal lab studies and well appearance.
Keywords: bacterial meningitis; neonates; young infants; serious bacterial infection; laboratory abnormalities bacterial meningitis; neonates; young infants; serious bacterial infection; laboratory abnormalities

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MDPI and ACS Style

Kotzbauer, D.; Travers, C.; Shapiro, C.; Charbonnet, M.; Cooley, A.; Andresen, D.; Frank, G. Etiology and Laboratory Abnormalities in Bacterial Meningitis in Neonates and Young Infants. Clin. Pract. 2017, 7, 943. https://doi.org/10.4081/cp.2017.943

AMA Style

Kotzbauer D, Travers C, Shapiro C, Charbonnet M, Cooley A, Andresen D, Frank G. Etiology and Laboratory Abnormalities in Bacterial Meningitis in Neonates and Young Infants. Clinics and Practice. 2017; 7(2):943. https://doi.org/10.4081/cp.2017.943

Chicago/Turabian Style

Kotzbauer, David, Curtis Travers, Craig Shapiro, Margaux Charbonnet, Anthony Cooley, Deborah Andresen, and Gary Frank. 2017. "Etiology and Laboratory Abnormalities in Bacterial Meningitis in Neonates and Young Infants" Clinics and Practice 7, no. 2: 943. https://doi.org/10.4081/cp.2017.943

APA Style

Kotzbauer, D., Travers, C., Shapiro, C., Charbonnet, M., Cooley, A., Andresen, D., & Frank, G. (2017). Etiology and Laboratory Abnormalities in Bacterial Meningitis in Neonates and Young Infants. Clinics and Practice, 7(2), 943. https://doi.org/10.4081/cp.2017.943

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