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Case Report

Uterine Epithelioid Trophoblastic Tumor in a 44-Year-Old Woman: A Diagnostic Dilemma

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1-st Surgical Oncology Unit, Regional Institute of Oncology, General Henri Mathias Berthelot 2-4, 700483 Iasi, Romania
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Grigore T. Popa, Surgical Department, University of Medicine and Pharmacy, 700115 Iasi, Romania
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Oncology Department, Regional Institute of Oncology, 700115 Iasi, Romania
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Radiology Department, Regional Institute of Oncology, 700115 Iasi, Romania
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Pathology Department, Regional Institute of Oncology, 700115 Iasi, Romania
*
Author to whom correspondence should be addressed.
Academic Editor: José I. López
Clin. Pract. 2021, 11(3), 631-639; https://doi.org/10.3390/clinpract11030078
Received: 13 July 2021 / Revised: 25 August 2021 / Accepted: 8 September 2021 / Published: 13 September 2021
Background: Epithelioid trophoblastic tumor (ETT) is a rare and newly defined disease, which most commonly occurs in women of reproductive age and can be a sequela of any gestational event. ETT can be present in both intrauterine and extrauterine sites. Case report: A woman of reproductive age, without specific comorbidities and with a single pregnancy and natural childbirth eight years ago, was diagnosed initially with poorly differentiated pleomorphic leiomyosarcoma on the hemostatic uterine curettage. Conclusion: Our case highlights that ETT presents a diagnostic challenge due to its rarity and histologic resemblance to other pathologies. Misdiagnosis delays effective treatment and affects survival. To date, only 8 cases of ETT of the uterus without previous gestational event and normal human chorionic gonadotropin (β-HCG) levels in a 60-year literature survey have been reported. View Full-Text
Keywords: epithelioid trophoblastic tumor; pleomorphic leiomyosarcoma; vaginal bleeding epithelioid trophoblastic tumor; pleomorphic leiomyosarcoma; vaginal bleeding
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MDPI and ACS Style

Aniţei, M.-G.; Lazăr, D.-E.; Pleşca, R.A.; Terinte, C.; Iulian, R.; Viorel, S. Uterine Epithelioid Trophoblastic Tumor in a 44-Year-Old Woman: A Diagnostic Dilemma. Clin. Pract. 2021, 11, 631-639. https://doi.org/10.3390/clinpract11030078

AMA Style

Aniţei M-G, Lazăr D-E, Pleşca RA, Terinte C, Iulian R, Viorel S. Uterine Epithelioid Trophoblastic Tumor in a 44-Year-Old Woman: A Diagnostic Dilemma. Clinics and Practice. 2021; 11(3):631-639. https://doi.org/10.3390/clinpract11030078

Chicago/Turabian Style

Aniţei, Maria-Gabriela, Diana-Elena Lazăr, Raluca A. Pleşca, Cristina Terinte, Radu Iulian, and Scripcariu Viorel. 2021. "Uterine Epithelioid Trophoblastic Tumor in a 44-Year-Old Woman: A Diagnostic Dilemma" Clinics and Practice 11, no. 3: 631-639. https://doi.org/10.3390/clinpract11030078

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