Next Article in Journal
Diagnostic and Therapeutic Challenges of Cerebral Venous Thrombosis in SARS-CoV-2 Infection: A Case Report and Review of Literature
Previous Article in Journal
Liver Cirrhosis and Hepatocellular Carcinoma Diagnosed from Chylothorax: A Case Report
Article

Postoperative Neutrophil to Lymphocyte Ratio as an Overall Mortality Midterm Prognostic Factor following OPCAB Procedures

1
Department of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, 61-848 Poznan, Poland
2
Department of Computer Science and Statistics, Poznan University of Medical Sciences, 60-806 Poznan, Poland
3
Department of Cardiology Medical University of Warsaw, 02-091 Warsaw, Poland
4
Ist Department of Cardiology, Poznan University of Medical Sciences, 61-848 Poznan, Poland
*
Author to whom correspondence should be addressed.
Clin. Pract. 2021, 11(3), 587-597; https://doi.org/10.3390/clinpract11030074
Received: 12 August 2021 / Revised: 30 August 2021 / Accepted: 31 August 2021 / Published: 3 September 2021
Background: Off-pump coronary artery bypass grafting (OPCAB) is believed to limit inflammatory reaction. Neutrophil to lymphocyte ratio (NLR) is one of the more common and easily accessible markers of inflammatory response. The aim of the study was to compare postoperative results of NLR with mid-term OPCAB results. Methods: In total, 224 patients (198 (88%) men and 26 (12%) women) with mean age 65 +/− 9 years who underwent OPCAB though median full sternotomy in our department in 2018 enrolled into the study. We scrupulously collected the postoperative mid-term results, including survival rate, clinical status and risk for major adverse events, and compared them with perioperative laboratory results. Results: A three-year follow-up was completed by 198 individuals (90% survival rate) with 12 (5%) showing major adverse cardiovascular (MACE) events risk. In the multivariable analysis, the laboratory parameters noticed on the 1st postoperative day were statistically significantly predictive of survival, including neutrophils (HR 1.59, 1.33–1.89 95%CI, p < 0.0001), platelets (HR 1.01, 1.01–1.01 95%CI, p = 0.0065), NLR (HR 1.47, 1.3–1.65 95%CI, p < 0.0001) and postoperative ejection fraction (HR 0.9, 0.87–0.95 95%CI, p < 0.0001). Conclusions: Postoperative NLR above 4.6, as an inflammatory reaction marker, is related to mid-term mortality in OPCAB patients. View Full-Text
Keywords: NLR 1; OPCAB 2; platelets 3; LVEF 4 NLR 1; OPCAB 2; platelets 3; LVEF 4
Show Figures

Figure 1

MDPI and ACS Style

Urbanowicz, T.; Michalak, M.; Gąsecka, A.; Perek, B.; Rodzki, M.; Bociański, M.; Straburzyńska-Migaj, E.; Jemielity, M. Postoperative Neutrophil to Lymphocyte Ratio as an Overall Mortality Midterm Prognostic Factor following OPCAB Procedures. Clin. Pract. 2021, 11, 587-597. https://doi.org/10.3390/clinpract11030074

AMA Style

Urbanowicz T, Michalak M, Gąsecka A, Perek B, Rodzki M, Bociański M, Straburzyńska-Migaj E, Jemielity M. Postoperative Neutrophil to Lymphocyte Ratio as an Overall Mortality Midterm Prognostic Factor following OPCAB Procedures. Clinics and Practice. 2021; 11(3):587-597. https://doi.org/10.3390/clinpract11030074

Chicago/Turabian Style

Urbanowicz, Tomasz, Michał Michalak, Aleksandra Gąsecka, Bartłomiej Perek, Michał Rodzki, Michał Bociański, Ewa Straburzyńska-Migaj, and Marek Jemielity. 2021. "Postoperative Neutrophil to Lymphocyte Ratio as an Overall Mortality Midterm Prognostic Factor following OPCAB Procedures" Clinics and Practice 11, no. 3: 587-597. https://doi.org/10.3390/clinpract11030074

Find Other Styles

Article Access Map by Country/Region

1
Back to TopTop