Panorama of Two Decades of Maternal Deaths in Brazil: Retrospective Ecological Time Series
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Population and Period
2.3. Data Sources and Variables
2.4. Data Management and Statistical Analysis
2.5. Ethical Considerations
3. Results
4. Discussion
4.1. Regional Inequalities
4.2. Risk Factors and Obstetric Causes
4.3. Health System Factors
4.4. Nursing Implications
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Public Involvement Statement
Guidelines and Standards Statement
Use of Artificial Intelligence
Conflicts of Interest
Abbreviations
| ICD-10 | Classification of Diseases—10th Revision |
| CSV | Comma Separated Values |
| FAPESPA | Fundação Amazônia de Amparo a Estudos e Pesquisas |
| ICU | Intensive Care Unit |
| LGBTQIA+ | Lesbian, Gay, Bisexual, Transgender, Queer or Questioning, Intersex, Asexual |
| MMR | Maternal mortality ratio |
| PNSI-LGBT | Política Nacional de Saúde Integral de Lésbicas, Gays, Bissexuais, Travestis e Transexuais |
| SIM | Sistema de Informações sobre Mortalidade |
| SINASC | Sistema de Informações sobre Nascidos Vivos |
| SUS | Sistema Único de Saúde |
| STROBE | Strengthening the Reporting of Observational Studies in Epidemiology |
| SDGs | Sustainable Development Goals |
| WHO | World Health Organization |
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| Category | Maternal Deaths (n=) | Maternal Deaths (%) |
|---|---|---|
| Region | ||
| Northern Region | 5147 | 12.6% |
| Northeast Region | 13,748 | 33.6% |
| Southeast Region | 14,129 | 34.5% |
| Southern Region | 4555 | 11.1% |
| Central-West Region | 3328 | 8.1% |
| Age | ||
| 10 to 14 years old | 346 | 0.8% |
| 15 to 19 years old | 5105 | 12.4% |
| 20 to 29 years old | 16,381 | 40% |
| 30 to 39 years old | 15,548 | 38% |
| 40 to 49 years old | 3418 | 8.3% |
| 50 to 59 years old | 85 | 0.2% |
| 70 to 79 years old | 1 | 0% |
| Age ignored | 23 | 0.1% |
| Race | ||
| White | 13,648 | 33.3% |
| Black | 4446 | 10.8% |
| Yellow | 123 | 0.3% |
| Brown | 19,773 | 48.3% |
| Indigenous | 566 | 1.3% |
| Ignored | 2351 | 5.7% |
| Marital status | ||
| Single | 20,579 | 50.3% |
| Married | 12,338 | 30.1% |
| Widower | 307 | 0.7% |
| Legally separated | 696 | 1.7% |
| Other | 3819 | 9.3% |
| Ignored | 3168 | 7.7% |
| Education | ||
| None | 1532 | 3.7% |
| 1 to 3 years | 4660 | 11.3% |
| 4 to 7 years | 9538 | 23.3% |
| 8 to 11 years | 12,151 | 29.7% |
| 9 to 11 years | 3 | 0.1% |
| 12 years and over | 3725 | 9.1% |
| Ignored | 9298 | 23.7% |
| Total | 40,907 | 100% |
| Category | Maternal Deaths (n=) | Maternal Deaths (%) | IC 95% |
|---|---|---|---|
| Chapter ICD-10 | |||
| I. Infectious diseases | 844 | 0.41% | 0.38–0.44 |
| II. Neoplasms | 10 | 0.4% | 0.002–0.008 |
| IV. Endocrine/metabolic | 1 | 0.5% | - |
| V. Mental disorders | 36 | 0.1% | 0.012–0.023 |
| XV. Pregnancy/childbirth/puerperium | 40,016 | 19.5% | 19.393–19.737 |
| Type of cause | |||
| Direct obstetric | 26,957 | 13.1% | 13.033–13.327 |
| Indirect obstetric | 12,665 | 6.1% | 6.088–6.297 |
| Obstetric unspecified | 1281 | 0.6% | 0.592–0.661 |
| Períod of death | |||
| Pregnancy/childbirth/abortion | 11,763 | 5.7% | 5.650–5.852 |
| Puerperium up to 42 days | 19,206 | 9.3% | 9.264–9.517 |
| Puerperium 43 days to <1 year | 1382 | 0.6% | 0.640–0.711 |
| Not in pregnancy or puerperium | 803 | 0.3% | 0.366–0.420 |
| Inconsistent period | 1976 | 0.9% | 0.924–1.009 |
| Not informed | 5777 | 2.8% | 2.753–2.896 |
| Place of occurrence | |||
| Hospital | 37,288 | 18.2% | 18.064–18.398 |
| Other establishments | 882 | 0.4% | 0.403–0.460 |
| Domicile | 1513 | 0.7% | 0.703–0.777 |
| Public road | 525 | 0.2% | 0.235–0.279 |
| Others | 648 | 0.3% | 0.292–0.341 |
| Ignored | 51 | 0.2% | 0.018–0.032 |
| Death investigated | |||
| Investigated with record | 23,123 | 11.3% | 11.168–11.443 |
| Investigated without a record | 3548 | 1.7% | 1.678–1.791 |
| Not investigated | 4482 | 2.1% | 2.128–2.255 |
| Not applicable | 9754 | 4.7% | 4.677–4.861 |
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dos Santos, G.G.; Vidotti, G.A.G.; Ichikawa, C.R.d.F.; Lima, C.F.; Dionizio, L.d.A.; Maia, J.S.; Zihlmann, K.F.; Neto, J.G.d.O.; Nascimento, W.S.M.; Cardoso, A.M.R.; et al. Panorama of Two Decades of Maternal Deaths in Brazil: Retrospective Ecological Time Series. Nurs. Rep. 2025, 15, 396. https://doi.org/10.3390/nursrep15110396
dos Santos GG, Vidotti GAG, Ichikawa CRdF, Lima CF, Dionizio LdA, Maia JS, Zihlmann KF, Neto JGdO, Nascimento WSM, Cardoso AMR, et al. Panorama of Two Decades of Maternal Deaths in Brazil: Retrospective Ecological Time Series. Nursing Reports. 2025; 15(11):396. https://doi.org/10.3390/nursrep15110396
Chicago/Turabian Styledos Santos, Gustavo Gonçalves, Giovana Aparecida Gonçalves Vidotti, Carolliny Rossi de Faria Ichikawa, Cindy Ferreira Lima, Leticia de Almeida Dionizio, Janize Silva Maia, Karina Franco Zihlmann, Joaquim Guerra de Oliveira Neto, Wágnar Silva Morais Nascimento, Alexandrina Maria Ramos Cardoso, and et al. 2025. "Panorama of Two Decades of Maternal Deaths in Brazil: Retrospective Ecological Time Series" Nursing Reports 15, no. 11: 396. https://doi.org/10.3390/nursrep15110396
APA Styledos Santos, G. G., Vidotti, G. A. G., Ichikawa, C. R. d. F., Lima, C. F., Dionizio, L. d. A., Maia, J. S., Zihlmann, K. F., Neto, J. G. d. O., Nascimento, W. S. M., Cardoso, A. M. R., Carvalho, J. M. d. N., Santa Rosa, P. L. F., Mouta, R. J. O., Reis, C. H. R., Aguiar, C. d. A., Santos, D. d. S., Silva, B. P. d., Silva, A. L. C. d., Nascimento, E. S. d., ... Pedraza, L. L. (2025). Panorama of Two Decades of Maternal Deaths in Brazil: Retrospective Ecological Time Series. Nursing Reports, 15(11), 396. https://doi.org/10.3390/nursrep15110396

