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Hematology Reports
Volume 6
Issue 3
10.4081/hr.2014.5572
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Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Hypotension associated with Advanced Hodgkin Lymphoma

by
Ankit Mangla
1,*,
Geetanjali Dang
1,
Hussein Hamad
1,
Roozbeh Mohajer
2,
Rosalind Catchatourian
2 and
Paula Kovarik
3
1
Department of Internal Medicine, John H. Stroger Jr. Hospital of Cook County, 1901 West Harrison Street, Chicago, IL 60612, USA
2
Division of Hematology and Oncology, John H. Stroger Jr. Hospital of Cook County, Chicago, IL, USA
3
Department of Pathology, John H. Stroger Jr. Hospital of Cook County, Chicago, IL, USA
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2014, 6(3), 5572; https://doi.org/10.4081/hr.2014.5572
Submission received: 26 July 2014 / Revised: 27 August 2014 / Accepted: 29 August 2014 / Published: 29 September 2014

Abstract

Hypotension is an extremely rare manifestation of Hodgkin lymphoma. We report the case of a patient who presented with new onset hypotension and was diagnosed with urosepsis and septic shock requiring pressor support for maintaining his blood pressure. computed tomography (CT) scan of abdomen showed liver lesions, which were new on comparison with a CT abdomen done 3 weeks back. Biopsy of the liver lesions and subsequently a bone marrow biopsy showed large atypical Reed-Sternberg cells, positive for CD15 and CD 30 and negative for CD45, CD3 and CD20 on immunohistochemical staining, hence establishing the diagnosis of Hodgkin lymphoma. The mechanism involved in Hodgkin lymphoma causing hypotension remains anecdotal, but since it is mostly seen in patients with advanced Hodgkin lymphoma, it is hypothetically related to a complex interaction between cytokines and mediators of vasodilatation. Here we review relevant literature pertaining to presentation and pathogenesis of this elusive and rare association.
Keywords: Hodgkin lymphoma; hypotension; liver metastasis Hodgkin lymphoma; hypotension; liver metastasis

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MDPI and ACS Style

Mangla, A.; Dang, G.; Hamad, H.; Mohajer, R.; Catchatourian, R.; Kovarik, P. Hypotension associated with Advanced Hodgkin Lymphoma. Hematol. Rep. 2014, 6, 5572. https://doi.org/10.4081/hr.2014.5572

AMA Style

Mangla A, Dang G, Hamad H, Mohajer R, Catchatourian R, Kovarik P. Hypotension associated with Advanced Hodgkin Lymphoma. Hematology Reports. 2014; 6(3):5572. https://doi.org/10.4081/hr.2014.5572

Chicago/Turabian Style

Mangla, Ankit, Geetanjali Dang, Hussein Hamad, Roozbeh Mohajer, Rosalind Catchatourian, and Paula Kovarik. 2014. "Hypotension associated with Advanced Hodgkin Lymphoma" Hematology Reports 6, no. 3: 5572. https://doi.org/10.4081/hr.2014.5572

APA Style

Mangla, A., Dang, G., Hamad, H., Mohajer, R., Catchatourian, R., & Kovarik, P. (2014). Hypotension associated with Advanced Hodgkin Lymphoma. Hematology Reports, 6(3), 5572. https://doi.org/10.4081/hr.2014.5572

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