Hairy Cell Leukemia: A Differential Diagnosis of Hepatitis B-Associated Aplastic Anemia and Syphilis
Abstract
1. Introduction
2. Case Description
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Test | Baseline Result | Follow Up Result | Reference Range |
---|---|---|---|
WBC × 109/L † | 0.7 | 1.52 | 4.1–11.0 |
Lymphocytes × 109/L | 0.6 (74.5%) | 1.41 (92.8%) | 0.6–4.1 (20–40%) |
Granulocytes × 109/L | 0.1 (20.4%) | 0.08 (5%) | 2.0–7.8 (54–76%) |
Monocytes × 109/L | 0.01 (1.2%) | 0.02 (1.5%) | 0.10–1.0 (2–10%) |
Eosinophils × 109/L | 0.01 (1.0%) | 0.01 (0.5%) | 0.0–0.6 (0–6%) |
Basophils × 109/L | 0.0 (0.1%) | 0.0 (0.2%) | 0.0–0.1 (0–1%) |
MID cells × 109/L | 0.0 (5.1%) | 0.0 (0.1%) | 0.0–0.1 (0–1%) |
Erythrocytes × 1012/L | 1.18 | 1.92 | 4.6–6.3 |
Hemoglobin, g/L | 39 | 66 | 140–180 |
Hematocrit, l/L | 0.13 | 0.21 | 0.40–0.51 |
MCV fl ╣ | 109 | 110 | 82–98 |
MCH pg ╧ | 33.1 | 34.6 | 26.0–32.0 |
MCHC g/L ¥ | 304 | 314 | 300–360 |
RWD% ≠ | 21.3 | 26.3 | 11.5–14.5 |
Platelets × 109/L | 30 | 18 | 140–440 |
Sedimentation rate mm | - | 28 | 0–15 |
Glucose, mmol/L | 8.15 | 4.2 | 4.1–5.9 |
Urea, mmol/L | 4.7 | 4.2 | 2.8–7.2 |
Creatinine, µmol/L | 82.0 | 73.0 | 74–110 |
Albumin, g/L | 32 | 38 | 36–52 |
Protein total, g/L | 75 | 63 | 66–83 |
Bilirubin total, µmol/L | 16.0 | 18.8 | 5.0–21.0 |
Bilirubin direct, µmol/L | 4.5 | 4.4 | 0.0–3.4 |
C-reactive protein, mg/L | 14.0 | 0.14 | 0.0–0.50 |
ASAT U/L ‡ | 12 | 7 | 0–50 |
ALAT U/L # | 12 | 10 | 0–50 |
GGT U/L § | 21 | 25 | 0–55 |
α-Amylase, U/L | 34 | 50 | 28–100 |
Alkaline phosphatase, U/L | 39 | 33 | 30–120 |
Lipase, U/L | 12.0 | 15.5 | 0–67 |
Potassium, mmol/L | 3.9 | 4.0 | 3.5–5.1 |
Sodium, mmol/L | 136 | 138 | 136–146 |
Chloride, mmol/L | 104 | 105 | 98–111 |
Lactatdehydrogenase, U/L | 86 | - | 0–248 |
Ferritin, ng/mL | 442.6 | - | 20–250 |
aPTT, s ₽ | - | 29.5 | 26.4–36.8 |
Fibrinogen, g/L | 5.0 | 3.0 | 1.5–4.5 |
Prothrombin time, s | 16.9 | 13.1 | 8.0–13.2 |
INR Ω | 1.55 | 1.18 | 0.8–1.2 |
Viral Infection Markers | Result | Reference Range |
---|---|---|
HBs-Ag ╧ | 2200 IU/mL | 0.005–150 IU/mL |
HBe-Ag § | negative | |
Anti-HBe Ab | positive | |
Anti-HDV Ab ¥ (total) | negative | |
Anti-HCV Ab Ω (total) | negative | |
HIV1/2 ≠ | negative | |
HBV DNA ‡ | 1,191,000 copies/mL | not detected |
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Kindekov, I.; Beleva, E.; Kadish, M.; Ionchev, I.; Semerdzhieva, N. Hairy Cell Leukemia: A Differential Diagnosis of Hepatitis B-Associated Aplastic Anemia and Syphilis. Hematol. Rep. 2025, 17, 13. https://doi.org/10.3390/hematolrep17020013
Kindekov I, Beleva E, Kadish M, Ionchev I, Semerdzhieva N. Hairy Cell Leukemia: A Differential Diagnosis of Hepatitis B-Associated Aplastic Anemia and Syphilis. Hematology Reports. 2025; 17(2):13. https://doi.org/10.3390/hematolrep17020013
Chicago/Turabian StyleKindekov, I., E. Beleva, M. Kadish, I. Ionchev, and N. Semerdzhieva. 2025. "Hairy Cell Leukemia: A Differential Diagnosis of Hepatitis B-Associated Aplastic Anemia and Syphilis" Hematology Reports 17, no. 2: 13. https://doi.org/10.3390/hematolrep17020013
APA StyleKindekov, I., Beleva, E., Kadish, M., Ionchev, I., & Semerdzhieva, N. (2025). Hairy Cell Leukemia: A Differential Diagnosis of Hepatitis B-Associated Aplastic Anemia and Syphilis. Hematology Reports, 17(2), 13. https://doi.org/10.3390/hematolrep17020013