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Article

Health Status and Quality of Life in Patients with Severe Hemophilia A: A Cross-Sectional Survey

1
Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2
Health Equity Research Center, Tehran University of Medical Science, Tehran, Iran
3
Department of Health Economics, National Institute for Health Research, Tehran University of Medical Science, Tehran, Iran
4
Department of Physiotherapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2019, 11(2), 7894; https://doi.org/10.4081/hr.2019.7894
Submission received: 29 September 2018 / Revised: 30 January 2019 / Accepted: 19 February 2019 / Published: 14 June 2019

Abstract

Among different groups of hemophiliacs, those suffering from Severe Hemophilia A (SHA) are most vulnerable to the complications of the disease. This study investigated the Health-Related Quality of Life (HR-QoL) among adult patients with SHA. A cross-sectional study was designed to gather demographic and clinical information from adult patients with SHA. Patients with inhibitors were excluded. The remaining were asked to complete the HR-QoL questionnaire after being examined for joint health using the Hemophilia Joint HealthScore (HJHS). The HR-QoL and joint conditions were measured in 38 patients. The mean EQ-5D value scores were 0.46 (SD = 0.23) while the mean Visual Analogous Scale score was 50 (SD = 18.7). The clinical examination of patients indicated that the HJHS were as follows: eight patients had a score of 55–75, 12 patients had a score of 40–55, 7 of them (25–40) and 11 patients had a score of 10–25. The results obtained from this study showed that HR-QoL in hemophilia patients was considerably low. Pain, anxiety/depression, and motion limitations were the main causes of the disutility for these patients respectively.
Keywords: hemophilia; health-related quality of life; hemophilia joint health score; EQ-5D hemophilia; health-related quality of life; hemophilia joint health score; EQ-5D

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MDPI and ACS Style

Davari, M.; Gharibnaseri, Z.; Ravanbod, R.; Sadeghi, A. Health Status and Quality of Life in Patients with Severe Hemophilia A: A Cross-Sectional Survey. Hematol. Rep. 2019, 11, 7894. https://doi.org/10.4081/hr.2019.7894

AMA Style

Davari M, Gharibnaseri Z, Ravanbod R, Sadeghi A. Health Status and Quality of Life in Patients with Severe Hemophilia A: A Cross-Sectional Survey. Hematology Reports. 2019; 11(2):7894. https://doi.org/10.4081/hr.2019.7894

Chicago/Turabian Style

Davari, Majid, Zahra Gharibnaseri, Roya Ravanbod, and Abolfazl Sadeghi. 2019. "Health Status and Quality of Life in Patients with Severe Hemophilia A: A Cross-Sectional Survey" Hematology Reports 11, no. 2: 7894. https://doi.org/10.4081/hr.2019.7894

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