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Infectious Disease Reports
Volume 10
Issue 3
10.4081/idr.2018.7725
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Infectious Disease Reports is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Transplacental Transmission: A Rare Case of Ebola Virus Transmission

by
Lawrence Okoror
1,*,
Abdul Kamara
2,
Brima Kargbo
2,
James Bangura
2 and
Mat Lebby
2
1
World Health Organization and Federal University, Oye-Ekiti, Nigeria
2
Ministry of Health and Sanitation, Freetown, Sierra Leone
*
Author to whom correspondence should be addressed.
Infect. Dis. Rep. 2018, 10(3), 7725; https://doi.org/10.4081/idr.2018.7725
Submission received: 18 April 2018 / Revised: 18 June 2018 / Accepted: 19 June 2018 / Published: 5 December 2018

Abstract

During the mid-transmission period of the Ebola virus disease (EVD) outbreak in Sierra Leone, a 19-year-old pregnant woman, who was a petty trader in a health facility in Freetown, noticing no fetal movement for the past 3 days, reported to a health facility. Medical history and laboratory testing showed no abnormalities except that she was positive for sickle cell. She was not known to any surveillance team of having any epidemiological link to EVD case. She was induced with oral medications as well as IV infusion. EVD test showed that the fetus was positive to EVD with a high threshold value of 21, while the woman was negative for EVD with a threshold value of 42. The woman was positive to EVD IgG but negative to EVD IgM by ELISA technique. This is a rare EVD case in the period of medium transmission. We conclude that the woman may have come into contact with a low dose of virus not enough to cause a full blown EVD and that her immune system was able to stop the virus from further replication.
Keywords: EVD; fetus; still birth; IgG; IgM; PCR EVD; fetus; still birth; IgG; IgM; PCR

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MDPI and ACS Style

Okoror, L.; Kamara, A.; Kargbo, B.; Bangura, J.; Lebby, M. Transplacental Transmission: A Rare Case of Ebola Virus Transmission. Infect. Dis. Rep. 2018, 10, 7725. https://doi.org/10.4081/idr.2018.7725

AMA Style

Okoror L, Kamara A, Kargbo B, Bangura J, Lebby M. Transplacental Transmission: A Rare Case of Ebola Virus Transmission. Infectious Disease Reports. 2018; 10(3):7725. https://doi.org/10.4081/idr.2018.7725

Chicago/Turabian Style

Okoror, Lawrence, Abdul Kamara, Brima Kargbo, James Bangura, and Mat Lebby. 2018. "Transplacental Transmission: A Rare Case of Ebola Virus Transmission" Infectious Disease Reports 10, no. 3: 7725. https://doi.org/10.4081/idr.2018.7725

APA Style

Okoror, L., Kamara, A., Kargbo, B., Bangura, J., & Lebby, M. (2018). Transplacental Transmission: A Rare Case of Ebola Virus Transmission. Infectious Disease Reports, 10(3), 7725. https://doi.org/10.4081/idr.2018.7725

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