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Case Report

Miller Fisher Syndrome with Sinus Arrest

1
Course of Neurology, Department of Health, Faculty of Health Sciences,Tsukuba University of Technology, Japan
2
Department of Neurology, Tsukuba Memorial Hospital, Japan
3
Department of Public Health, School of Medicine, Dokkyo Medical University, Japan
4
Department of Cardiology, Tsukuba Memorial Hospital, Japan
5
Department of Neurology, Faculty of Medicine, Kindai University, Japan
6
Department of Neurology, Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, Japan
*
Author to whom correspondence should be addressed.
Neurol. Int. 2017, 9(3), 36-37; https://doi.org/10.4081/ni.2017.7312
Received: 14 July 2017 / Revised: 14 July 2017 / Accepted: 23 July 2017 / Published: 29 August 2017
Dysautonomia in Guillain-Barre syndrome (GBS) rarely causes serious cardiovascular complications, such as sinus arrest. Miller Fisher syndrome (MFS) is recognized as a variant of GBS. There have been few reports regarding the association between MFS and dysautonomia. We describe a case of a 68-year-old man with ophthalmoplegia, bulbar palsy, truncal ataxia, and areflexia. He was diagnosed with MFS because he exhibited the classical clinical triad and had elevated serum anti- GQ1b immunoglobulin G levels. A magnetic resonance imaging scan of his head was normal. His 24-hour Holter recording showed sinus arrest. He was treated with intravenous immunoglobulin, whereupon his symptoms gradually improved. This included the sinus arrest, which was considered a symptom of dysautonomia in MFS. Therefore, clinicians should be mindful of dysautonomia not only in GBS patients, but also in cases of MFS.
Keywords: Miller Fisher syndrome; Guillain- Barre syndrome; Dysautonomia; Sinus arrest Miller Fisher syndrome; Guillain- Barre syndrome; Dysautonomia; Sinus arrest
MDPI and ACS Style

Shiraiwa, N.; Umesawa, M.; Hoshino, S.; Enomoto, T.; Kusunoki, S.; Tamaoka, A.; Ohkoshi, N. Miller Fisher Syndrome with Sinus Arrest. Neurol. Int. 2017, 9, 36-37. https://doi.org/10.4081/ni.2017.7312

AMA Style

Shiraiwa N, Umesawa M, Hoshino S, Enomoto T, Kusunoki S, Tamaoka A, Ohkoshi N. Miller Fisher Syndrome with Sinus Arrest. Neurology International. 2017; 9(3):36-37. https://doi.org/10.4081/ni.2017.7312

Chicago/Turabian Style

Shiraiwa, Nobuko, Mitsumasa Umesawa, Sachiko Hoshino, Tsuyoshi Enomoto, Susumu Kusunoki, Akira Tamaoka, and Norio Ohkoshi. 2017. "Miller Fisher Syndrome with Sinus Arrest" Neurology International 9, no. 3: 36-37. https://doi.org/10.4081/ni.2017.7312

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