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Neurology International
Volume 8
Issue 3
10.4081/ni.2016.6812
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Neurology International is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Article

Neurosyphilis with Normal Pressure Hydrocephalus and Dementia Paralytica: Serial Clinical, Laboratory and Radiological Correlations in the 21st Century

by
Kamille Abdool
1,
Karan Seegobin
1,
Kanterpersad Ramcharan
1,*,
Adrian Alexander
1,
Leandra Julien-Legen
1,
Stanley Lawrence Giddings
2,
Samuel Aboh
2 and
Fidel Rampersad
3
1
Neurology Unit, San Fernando Teaching Hospital, University of the West Indies, Trinidad and Tobago
2
Infectious Disease Unit, San Fernando Teaching Hospital, University of the West Indies, Trinidad and Tobago
3
Radiology Department, University of the West Indies, Trinidad and Tobago
*
Author to whom correspondence should be addressed.
Neurol. Int. 2016, 8(3), 6812; https://doi.org/10.4081/ni.2016.6812
Submission received: 31 July 2016 / Revised: 4 August 2016 / Accepted: 8 August 2016 / Published: 3 October 2016

Abstract

We report a case of a 46-year-old man presenting with a progressive cognitive decline, ataxic gait, urinary incontinence for 4 months and neuroimaging consistent with normal pressure hydrocephalus. The atypical presentation of a progressively worsening dysphasia and a right hemiparesis dismissed as a vascular event 1 month earlier associated with normal pressure hydrocephalus prompted further investigations confirming neurosyphilis also manifesting as dementia paralytica. Treatment using consensus guidelines led to resumption of activities of daily living. Neurosyphilis, considered rare in the neuroimaging era, must still be considered a reversible cause of dementia and other neurological manifestations in contemporary neurological practice.
Keywords: Neurosyphilis; Neuroradiology; Normal Pressure Hydrocephalus; Syphilis Neurosyphilis; Neuroradiology; Normal Pressure Hydrocephalus; Syphilis

Share and Cite

MDPI and ACS Style

Abdool, K.; Seegobin, K.; Ramcharan, K.; Alexander, A.; Julien-Legen, L.; Giddings, S.L.; Aboh, S.; Rampersad, F. Neurosyphilis with Normal Pressure Hydrocephalus and Dementia Paralytica: Serial Clinical, Laboratory and Radiological Correlations in the 21st Century. Neurol. Int. 2016, 8, 6812. https://doi.org/10.4081/ni.2016.6812

AMA Style

Abdool K, Seegobin K, Ramcharan K, Alexander A, Julien-Legen L, Giddings SL, Aboh S, Rampersad F. Neurosyphilis with Normal Pressure Hydrocephalus and Dementia Paralytica: Serial Clinical, Laboratory and Radiological Correlations in the 21st Century. Neurology International. 2016; 8(3):6812. https://doi.org/10.4081/ni.2016.6812

Chicago/Turabian Style

Abdool, Kamille, Karan Seegobin, Kanterpersad Ramcharan, Adrian Alexander, Leandra Julien-Legen, Stanley Lawrence Giddings, Samuel Aboh, and Fidel Rampersad. 2016. "Neurosyphilis with Normal Pressure Hydrocephalus and Dementia Paralytica: Serial Clinical, Laboratory and Radiological Correlations in the 21st Century" Neurology International 8, no. 3: 6812. https://doi.org/10.4081/ni.2016.6812

APA Style

Abdool, K., Seegobin, K., Ramcharan, K., Alexander, A., Julien-Legen, L., Giddings, S. L., Aboh, S., & Rampersad, F. (2016). Neurosyphilis with Normal Pressure Hydrocephalus and Dementia Paralytica: Serial Clinical, Laboratory and Radiological Correlations in the 21st Century. Neurology International, 8(3), 6812. https://doi.org/10.4081/ni.2016.6812

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