Next Article in Journal
Reverse Takotsubo Syndrome, a Case Report of a Rare Cause for Postpartum Heart Failure
Previous Article in Journal
Lamin-A/C Variants Found in Patients with Cardiac Conduction Disease Reduce Sodium Currents
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Cardiogenetics
Volume 8
Issue 1
10.4081/cardiogenetics.2018.7262
cardiogenetics-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Cardiogenetics is published by MDPI from Volume 10 Issue 2 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

A Therapeutic Genome Editing Primer for Cardiologists

by
Martina Caiazza
*,
Daniele Masarone
and
Giuseppe Limongelli
Department of Cardiology, Università Degli Studi Della Campania, Luigi Vanvitelli, Naples, Italy
*
Author to whom correspondence should be addressed.
Cardiogenetics 2018, 8(1), 7262; https://doi.org/10.4081/cardiogenetics.2018.7262
Submission received: 27 December 2017 / Revised: 15 March 2018 / Accepted: 24 April 2018 / Published: 16 May 2018

Abstract

Genome editing, or genome engineering is a type of genetic engineering in which DNA is inserted, deleted or replaced in the genome of a living organism using engineered nucleases, or molecular scissors. Genome editing is being rapidly adopted into all fields of biomedical research, including the cardiovascular field, where it has facilitated a greater understanding of lipid metabolism, electrophysiology, cardiomyopathies, and other cardiovascular disorders, has helped to create a wider variety of cellular and animal models, and has opened the door to a new class of therapies. In this review, we discuss the applications of in vivo genome-editing therapies for cardiovascular disorder.
Keywords: therapeutic genome editing; cardiovascular disease therapeutic genome editing; cardiovascular disease

Share and Cite

MDPI and ACS Style

Caiazza, M.; Masarone, D.; Limongelli, G. A Therapeutic Genome Editing Primer for Cardiologists. Cardiogenetics 2018, 8, 7262. https://doi.org/10.4081/cardiogenetics.2018.7262

AMA Style

Caiazza M, Masarone D, Limongelli G. A Therapeutic Genome Editing Primer for Cardiologists. Cardiogenetics. 2018; 8(1):7262. https://doi.org/10.4081/cardiogenetics.2018.7262

Chicago/Turabian Style

Caiazza, Martina, Daniele Masarone, and Giuseppe Limongelli. 2018. "A Therapeutic Genome Editing Primer for Cardiologists" Cardiogenetics 8, no. 1: 7262. https://doi.org/10.4081/cardiogenetics.2018.7262

APA Style

Caiazza, M., Masarone, D., & Limongelli, G. (2018). A Therapeutic Genome Editing Primer for Cardiologists. Cardiogenetics, 8(1), 7262. https://doi.org/10.4081/cardiogenetics.2018.7262

Article Metrics

Back to TopTop