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Review

Cardiac Involvement in Autosomal Dominant Polycystic Kidney Disease

Department of Advanced Biomedical Sciences, Federico II University, 80131 Naples, Italy
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Academic Editor: Giuseppe Limongelli
Cardiogenetics 2021, 11(2), 39-49; https://doi.org/10.3390/cardiogenetics11020006
Received: 17 March 2021 / Revised: 5 April 2021 / Accepted: 16 April 2021 / Published: 20 April 2021
Cardiovascular disorders are the main complication in autosomal dominant polycystic kidney disease (ADPKD). contributing to both morbidity and mortality. This review considers clinical studies unveiling cardiovascular features in patients with ADPKD. Additionally, it focuses on basic science studies addressing the dysfunction of the polycystin proteins located in the cardiovascular system as a contributing factor to cardiovascular abnormalities. In particular, the effects of polycystin proteins’ deficiency on the cardiomyocyte function have been considered. View Full-Text
Keywords: autosomal dominant polycystic kidney disease; polycystin; cardiomyocyte function; left ventricular diastolic function autosomal dominant polycystic kidney disease; polycystin; cardiomyocyte function; left ventricular diastolic function
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MDPI and ACS Style

Spinelli, L.; Giugliano, G.; Esposito, G. Cardiac Involvement in Autosomal Dominant Polycystic Kidney Disease. Cardiogenetics 2021, 11, 39-49. https://doi.org/10.3390/cardiogenetics11020006

AMA Style

Spinelli L, Giugliano G, Esposito G. Cardiac Involvement in Autosomal Dominant Polycystic Kidney Disease. Cardiogenetics. 2021; 11(2):39-49. https://doi.org/10.3390/cardiogenetics11020006

Chicago/Turabian Style

Spinelli, Letizia; Giugliano, Giuseppe; Esposito, Giovanni. 2021. "Cardiac Involvement in Autosomal Dominant Polycystic Kidney Disease" Cardiogenetics 11, no. 2: 39-49. https://doi.org/10.3390/cardiogenetics11020006

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