Genetic Susceptibility to SARS-CoV-2: From the Nehandertal Age to 2020
References
- Wang, D.; Hu, B.; Hu, C.; Zhu, F.; Liu, X.; Zhang, J.; Wang, B.; Xiang, H.; Cheng, Z.; Xiong, Y.; et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA 2020, 11, 1061–1069. [Google Scholar] [CrossRef] [PubMed]
- Chan, J.F.; Yuan, S.; Kok, K.H.; To, K.K.; Chu, H.; Yang, J.; Xing, F.; Liu, J.; Yip, C.C.; Poon, R.W.; et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: A study of a family cluster. Lancet 2020, 10223, 514–523. [Google Scholar] [CrossRef] [Green Version]
- Guan, W.J.; Ni, Z.Y.; Hu, Y.; Liang, W.H.; Ou, C.Q.; He, J.X.; Liu, L.; Shan, H.; Lei, C.L.; Hui, D.S.C.; et al. China Medical Treatment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China. N. Engl. J. Med. 2020, 18, 1708–1720. [Google Scholar] [CrossRef]
- Zhou, F.; Yu, T.; Du, R.; Fan, G.; Liu, Y.; Liu, Z.; Xiang, J.; Wang, Y.; Song, B.; Gu, X.; et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan; China: A retrospective cohort study. Lancet 2020, 10229, 1054–1062. [Google Scholar] [CrossRef]
- Science. Available online: https://www.sciencemag.org/news/2020/03/how-sick-will-coronavirus-make-you-answer-may-be-your-genes (accessed on 27 March 2020).
- Zeberg, H.; Pääbo, S. The major genetic risk factor for severe COVID-19 is inherited from Neanderthals. Nature 2020, 7835, 610–612. [Google Scholar] [CrossRef] [PubMed]
- Ellinghaus, D.; Degenhardt, F.; Bujanda, L.; Buti, M.; Albillos, A.; Invernizzi, P.; Fernández, J.; Prati, D.; Baselli, G.; Asselta, R.; et al. Severe Covid-19 GWAS Group. Genomewide Association Study of Severe Covid-19 with Respiratory Failure. N. Engl. J. Med. 2020, 16, 1522–1534. [Google Scholar] [CrossRef]
- Green, R.E.; Krause, J.; Briggs, A.W.; Maricic, T.; Stenzel, U.; Kircher, M.; Patterson, N.; Li, H.; Zhai, W.; Fritz, M.H.; et al. A draft sequence of the Neandertal genome. Science 2010, 5979, 710–722. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Sankararaman, S.; Patterson, N.; Li, H.; Pääbo, S.; Reich, D. The date of interbreeding between Neandertals and modern humans. PLoS Genet. 2012, 10, e1002947. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Sankararaman, S.; Mallick, S.; Dannemann, M.; Prüfer, K.; Kelso, J.; Pääbo, S.; Patterson, N.; Reich, D. The genomic landscape of Neanderthal ancestry in present-day humans. Nature 2014, 7492, 354–357. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Public Health England. Available online: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/908434/Disparities_in_the_risk_and_outcomes_of_COVID_August_2020_update.pdf (accessed on 1 August 2020).
- Nguyen, A.; David, J.K.; Maden, S.K.; Wood, M.A.; Weeder, B.R.; Nellore, A.; Thompson, R.F. Human Leukocyte Antigen Susceptibility Map for Severe Acute Respiratory Syndrome Coronavirus 2. J. Virol. 2020, 13, e00510-20. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Lin, M.; Tseng, H.K.; Trejaut, J.A.; Lee, H.L.; Loo, J.H.; Chu, C.C.; Chen, P.J.; Su, Y.W.; Lim, K.H.; Tsai, Z.U.; et al. Association of HLA class I with severe acute respiratory syndrome coronavirus infection. BMC Med. Genet. 2003, 12, 9. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Sibener, L.V.; Fernandes, R.A.; Kolawole, E.M.; Carbone, C.B.; Liu, F.; McAffee, D.; Birnbaum, M.E.; Yang, X.; Su, L.F.; Yu, W.; et al. Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell 2018, 3, 672–687.e27. [Google Scholar] [CrossRef] [PubMed]
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Amodio, F.; Caiazza, M.; Calabrò, P.; Limongelli, G. Genetic Susceptibility to SARS-CoV-2: From the Nehandertal Age to 2020. Cardiogenetics 2021, 11, 28-30. https://doi.org/10.3390/cardiogenetics11010004
Amodio F, Caiazza M, Calabrò P, Limongelli G. Genetic Susceptibility to SARS-CoV-2: From the Nehandertal Age to 2020. Cardiogenetics. 2021; 11(1):28-30. https://doi.org/10.3390/cardiogenetics11010004
Chicago/Turabian StyleAmodio, Federica, Martina Caiazza, Paolo Calabrò, and Giuseppe Limongelli. 2021. "Genetic Susceptibility to SARS-CoV-2: From the Nehandertal Age to 2020" Cardiogenetics 11, no. 1: 28-30. https://doi.org/10.3390/cardiogenetics11010004