Next Article in Journal
Budget Impact of Antimicrobial Wound Dressings in the Treatment of Venous Leg Ulcers in the German Outpatient Care Sector: A Budget Impact Analysis
Previous Article in Journal
Establishing the Cost of Implementing a Performance-Based, Managed Entry Agreement for a Hypothetical CAR T-Cell Therapy
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JMAHP
Volume 6
Issue 1
10.1080/20016689.2018.1517573
jmahp-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Journal of Market Access & Health Policy (JMAHP) is published by MDPI from Volume 12 Issue 1 (2024). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Taylor & Francis.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Health Related Quality of Life in Patients Having Schizophrenia Negative Symptoms—A Systematic Review

by
Chiraz Azaiez
1,
Aurélie Millier
2,*,
Christophe Lançon
3,
Emilie Clay
2,
Pascal Auquier
1,
Pierre-Michel Llorca
4 and
Mondher Toumi
1
1
Public Health Department–Research Unit EA 3279, Aix-Marseille University, Marseille, France
2
Creativ-Ceutical, Paris, France
3
Psychiatry Department, Marseille University Hospital, Marseille, France
4
CHU Clermont-Ferrand, Department of Psychiatry, University of Clermont Auvergne, Clermont-Ferrand, France
*
Author to whom correspondence should be addressed.
J. Mark. Access Health Policy 2018, 6(1), 1517573; https://doi.org/10.1080/20016689.2018.1517573
Submission received: 14 May 2018 / Revised: 14 August 2018 / Accepted: 21 August 2018 / Published: 27 September 2018

Abstract

Background: Schizophrenia negative symptoms (SNS) contribute substantially to poor functional outcomes, loss in productivity and poor quality of life. It is unclear which instruments may be used for assessing quality of life in patients with SNS. Objective: The objective of this review was to identify instruments assessing health-related quality of life (HRQoL) validated in patients with SNS and to assess their level of validation. Data sources: We conducted a systematic literature review in Medline and the ISPOR database in March 2016 to identify studies on the quality of life in patients with SNS published by March 2016. Data extraction: Psychometric properties and validation steps. Data synthesis: After applying inclusion/exclusion criteria, 49 studies were selected for the analysis of HRQoL instruments; however, none of these instruments only addressed patients with SNS. Of these, 19 HRQoL instruments used in patients with schizophrenia or including patients with SNS among others, in the context of instrument validation, were identified (4 generic, 10 non-specific mental health, 5 schizophrenia-specific). Conclusion: No HRQoL instrument has been validated in patients with SNS only; for the remaining instruments identified, it remains unclear whether they were intended to capture HRQoL in patients with SNS.
Keywords: health related quality of life; negative symptoms; validation; instruments; psychometric properties; schizophrenia health related quality of life; negative symptoms; validation; instruments; psychometric properties; schizophrenia

Share and Cite

MDPI and ACS Style

Azaiez, C.; Millier, A.; Lançon, C.; Clay, E.; Auquier, P.; Llorca, P.-M.; Toumi, M. Health Related Quality of Life in Patients Having Schizophrenia Negative Symptoms—A Systematic Review. J. Mark. Access Health Policy 2018, 6, 1517573. https://doi.org/10.1080/20016689.2018.1517573

AMA Style

Azaiez C, Millier A, Lançon C, Clay E, Auquier P, Llorca P-M, Toumi M. Health Related Quality of Life in Patients Having Schizophrenia Negative Symptoms—A Systematic Review. Journal of Market Access & Health Policy. 2018; 6(1):1517573. https://doi.org/10.1080/20016689.2018.1517573

Chicago/Turabian Style

Azaiez, Chiraz, Aurélie Millier, Christophe Lançon, Emilie Clay, Pascal Auquier, Pierre-Michel Llorca, and Mondher Toumi. 2018. "Health Related Quality of Life in Patients Having Schizophrenia Negative Symptoms—A Systematic Review" Journal of Market Access & Health Policy 6, no. 1: 1517573. https://doi.org/10.1080/20016689.2018.1517573

APA Style

Azaiez, C., Millier, A., Lançon, C., Clay, E., Auquier, P., Llorca, P. -M., & Toumi, M. (2018). Health Related Quality of Life in Patients Having Schizophrenia Negative Symptoms—A Systematic Review. Journal of Market Access & Health Policy, 6(1), 1517573. https://doi.org/10.1080/20016689.2018.1517573

Article Metrics

Back to TopTop