Synthesis and Rheological Characterization of a Novel Salecan Hydrogel

Zhang, Qinling; Ren, Teng; Gan, Jing; Sun, Lirong; Guan, Chenxia; Zhang, Qian; Pan, Shihui; Chen, Hao

doi:10.3390/pharmaceutics14071492

Open AccessArticle

Synthesis and Rheological Characterization of a Novel Salecan Hydrogel

by

Qinling Zhang

^1,†,

Teng Ren

^1,†,

Jing Gan

²,

Lirong Sun

¹,

Chenxia Guan

¹,

Qian Zhang

¹

,

Shihui Pan

¹ and

Hao Chen

^1,3,*

¹

Marine College, Shandong University (Weihai), No. 180 Wenhua West Road, Gao Strict, Weihai 264209, China

²

College of Life Sciences, Yantai University, No. 30 Qingquan Road, Laishan Strict, Yantai 264000, China

³

The Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, Jiangnan University, No. 1800 Lihu Road, Wuxi 214122, China

^*

Author to whom correspondence should be addressed.

^†

These authors contributed equally to this work.

Pharmaceutics 2022, 14(7), 1492; https://doi.org/10.3390/pharmaceutics14071492

Submission received: 20 June 2022 / Revised: 10 July 2022 / Accepted: 14 July 2022 / Published: 18 July 2022

(This article belongs to the Special Issue Recent Advances in Pharmaceutical Applications of Functionalized Polysaccharides and Their Derivatives)

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Abstract

Salecan (Sal) is a novel microbial polysaccharide. In the present research, thermal treatment was performed to fabricate Sal hydrogel. The effect of Sal concentration on water holding capacity, swelling properties, texture properties, and microstructure of the hydrogels was discussed. It was found that the equilibrium degree of swelling (EDS) of Sal hydrogels was above 1500%, inferred Sal was a highly hydrophilic polysaccharide. As Sal concentration increased from 3.5 to 8.0 wt%, the hardness increased from 0.88 to 2.07 N and the water hold capability (WHC) increased from 91.3% to 98.2%. Furthermore, the internal network structure of Sal hydrogel also became denser and more uniform. Rheological studies suggested that elastic hydrogel formed under the gelation process. All these results demonstrated that Sal hydrogel prepared by thermal treatment had good gelling properties, which opened up a new safe way for the preparation of Sal hydrogel and broadened the application range of Sal.

Keywords: Salecan; hydrogel; thermal treatment; rheological

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MDPI and ACS Style

Zhang, Q.; Ren, T.; Gan, J.; Sun, L.; Guan, C.; Zhang, Q.; Pan, S.; Chen, H. Synthesis and Rheological Characterization of a Novel Salecan Hydrogel. Pharmaceutics 2022, 14, 1492. https://doi.org/10.3390/pharmaceutics14071492

AMA Style

Zhang Q, Ren T, Gan J, Sun L, Guan C, Zhang Q, Pan S, Chen H. Synthesis and Rheological Characterization of a Novel Salecan Hydrogel. Pharmaceutics. 2022; 14(7):1492. https://doi.org/10.3390/pharmaceutics14071492

Chicago/Turabian Style

Zhang, Qinling, Teng Ren, Jing Gan, Lirong Sun, Chenxia Guan, Qian Zhang, Shihui Pan, and Hao Chen. 2022. "Synthesis and Rheological Characterization of a Novel Salecan Hydrogel" Pharmaceutics 14, no. 7: 1492. https://doi.org/10.3390/pharmaceutics14071492

APA Style

Zhang, Q., Ren, T., Gan, J., Sun, L., Guan, C., Zhang, Q., Pan, S., & Chen, H. (2022). Synthesis and Rheological Characterization of a Novel Salecan Hydrogel. Pharmaceutics, 14(7), 1492. https://doi.org/10.3390/pharmaceutics14071492

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Synthesis and Rheological Characterization of a Novel Salecan Hydrogel

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