Selected Medicines Used in Iontophoresis
Department of Medical Microbiology, Poznań University of Medical Sciences, Wieniawskiego 3, 61-712 Poznań, Poland
Pharmaceutics 2018, 10(4), 204; https://doi.org/10.3390/pharmaceutics10040204
Received: 19 September 2018 / Revised: 17 October 2018 / Accepted: 24 October 2018 / Published: 25 October 2018
(This article belongs to the Special Issue Iontophoresis for Drug Delivery and Non-Invasive Sampling Applications)
Iontophoresis is a non-invasive method of systemic and local drug delivery using an electric field. Iontophoresis enables diffusion of the selected drug via skin, mucosa, enamel, dentin, and other tissues. The amount of delivered therapeutic molecules is about 10–2000 times greater than conventional forms of delivery. Among other fields, this method is used in dentistry, ophthalmology, otorhinolaryngology, and dermatology. According to related literature, the most important drugs studied or administered by iontophoresis are: Local anesthetics, opioids, steroids, non-steroidal anti-inflammatory drugs, antibacterial drugs, antifungal drugs, antiviral drugs, anticancer drugs, fluorides, and vitamins. The present review covers current available data regarding the selected medicines used in iontophoresis. Furthermore, indications and conditions of iontophoresis application are reviewed.
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Keywords:
iontophoresis; drug delivery; dentistry; ophthalmology; local anaesthetics; non-steroid anti-inflammatory drugs; antibiotics; anticancer drugs
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Karpiński, T.M. Selected Medicines Used in Iontophoresis. Pharmaceutics 2018, 10, 204.
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