Next Article in Journal
Mechanisms of Adaptive Immunity to Porcine Reproductive and Respiratory Syndrome Virus
Previous Article in Journal
Characterization of Bacillus subtilis Viruses vB_BsuM-Goe2 and vB_BsuM-Goe3
Previous Article in Special Issue
Historical Perspectives on Flavivirus Research
Review

Zika Virus: Recent Advances towards the Development of Vaccines and Therapeutics

Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Academic Editor: Eric Freed
Viruses 2017, 9(6), 143; https://doi.org/10.3390/v9060143
Received: 18 April 2017 / Revised: 2 June 2017 / Accepted: 8 June 2017 / Published: 13 June 2017
(This article belongs to the Special Issue Advances in Flavivirus Research)
Zika is a rapidly emerging public health threat. Although clinical infection is frequently mild, significant neurological manifestations have been demonstrated in infants born to Zika virus (ZIKV) infected mothers. Due to the substantial ramifications of intrauterine infection, effective counter-measures are urgently needed. In order to develop effective anti-ZIKV vaccines and therapeutics, improved animal models and a better understanding of immunological correlates of protection against ZIKV are required. This review will summarize what is currently known about ZIKV, the clinical manifestations and epidemiology of Zika as well as, the development of animal models to study ZIKV infection, host immune responses against ZIKV, and the current state of development of vaccines and therapeutics against ZIKV. View Full-Text
Keywords: Zika virus; animal models; immunology; vaccines; congenital Zika syndrome Zika virus; animal models; immunology; vaccines; congenital Zika syndrome
MDPI and ACS Style

McArthur, M.A. Zika Virus: Recent Advances towards the Development of Vaccines and Therapeutics. Viruses 2017, 9, 143. https://doi.org/10.3390/v9060143

AMA Style

McArthur MA. Zika Virus: Recent Advances towards the Development of Vaccines and Therapeutics. Viruses. 2017; 9(6):143. https://doi.org/10.3390/v9060143

Chicago/Turabian Style

McArthur, Monica A. 2017. "Zika Virus: Recent Advances towards the Development of Vaccines and Therapeutics" Viruses 9, no. 6: 143. https://doi.org/10.3390/v9060143

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop