Next Article in Journal / Special Issue
Kaposi’s Sarcoma-Associated Herpesvirus ORF57 Protein: Exploiting All Stages of Viral mRNA Processing
Previous Article in Journal
Small Ruminant Lentiviruses (SRLVs) Break the Species Barrier to Acquire New Host Range
Previous Article in Special Issue
Nuclear Imprisonment: Viral Strategies to Arrest Host mRNA Nuclear Export
Article Menu

Export Article

Open AccessReview
Viruses 2013, 5(7), 1885-1900;

Baculovirus Nuclear Import: Open, Nuclear Pore Complex (NPC) Sesame

Department of Zoology, University of British Columbia, 6270 University Boulevard, Vancouver, British Columbia V6T 1Z4, Canada
Author to whom correspondence should be addressed.
Received: 30 May 2013 / Revised: 17 July 2013 / Accepted: 17 July 2013 / Published: 23 July 2013
(This article belongs to the Special Issue Viral Nuclear Import)
Full-Text   |   PDF [622 KB, uploaded 12 May 2015]   |  


Baculoviruses are one of the largest viruses that replicate in the nucleus of their host cells. During infection, the rod-shape, 250-nm long nucleocapsid delivers its genome into the nucleus. Electron microscopy evidence suggests that baculoviruses, specifically the Alphabaculoviruses (nucleopolyhedroviruses) and the Betabaculoviruses (granuloviruses), have evolved two very distinct modes for doing this. Here we review historical and current experimental results of baculovirus nuclear import studies, with an emphasis on electron microscopy studies employing the prototypical baculovirus Autographa californica multiple nucleopolyhedrovirus infecting cultured cells. We also discuss the implications of recent studies towards theories of nuclear transport mechanisms. View Full-Text
Keywords: baculovirus; AcMNPV; nuclear import; nuclear pore complex; viruses baculovirus; AcMNPV; nuclear import; nuclear pore complex; viruses

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Au, S.; Wu, W.; Panté, N. Baculovirus Nuclear Import: Open, Nuclear Pore Complex (NPC) Sesame. Viruses 2013, 5, 1885-1900.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top