Next Article in Journal
Spread of the Emerging Viral Hemorrhagic Septicemia Virus Strain, Genotype IVb, in Michigan, USA
Next Article in Special Issue
Regulatory T Cells in Arterivirus and Coronavirus Infections: Do They Protect Against Disease or Enhance it?
Previous Article in Journal
Pharmacological Inhibition of Feline Immunodeficiency Virus (FIV)
Previous Article in Special Issue
Evaluation of the Long-Term Effect of Air Filtration on the Occurrence of New PRRSV Infections in Large Breeding Herds in Swine-Dense Regions
Open AccessReview

Post-Transcriptional Control of Type I Interferon Induction by Porcine Reproductive and Respiratory Syndrome Virus in Its Natural Host Cells

1
Department of Biology and Microbiology, South Dakota State University, Brookings, SD 57007, USA
2
Department of Veterinary and Biomedical Sciences, South Dakota State University, Brookings, SD 57007, USA
*
Author to whom correspondence should be addressed.
Viruses 2012, 4(5), 725-733; https://doi.org/10.3390/v4050725
Received: 29 March 2012 / Revised: 18 April 2012 / Accepted: 24 April 2012 / Published: 2 May 2012
(This article belongs to the Special Issue Animal Arteriviruses and Coronaviruses)
Porcine reproductive and respiratory syndrome virus (PRRSV) is not only a poor inducer of type I interferon but also inhibits the efficient induction of type I interferon by porcine transmissible gastroenteritis virus (TGEV) and synthetic dsRNA molecules, Poly I:C. However, the mechanistic basis by which PRRSV interferes with the induction of type I interferon in its natural host cells remains less well defined. The purposes of this review are to summarize the key findings in supporting the post-transcriptional control of type I interferon in its natural host cells and to propose the possible role of translational control in the regulation of type I interferon induction by PRRSV. View Full-Text
Keywords: PRRSV; type I interferon; post-transcriptional regulation; translational control PRRSV; type I interferon; post-transcriptional regulation; translational control
MDPI and ACS Style

Wang, X.; Christopher-Hennings, J. Post-Transcriptional Control of Type I Interferon Induction by Porcine Reproductive and Respiratory Syndrome Virus in Its Natural Host Cells. Viruses 2012, 4, 725-733.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop