Genetic Profile of Rotavirus Type A in Children under 5 Years Old in Africa: A Systematic Review of Prevalence
Abstract
:1. Introduction
2. Materials and Methods
2.1. Search Strategy
2.2. Study Selection
2.3. Data Extraction and Quality Assessment
2.4. Statistical Analysis and Synthesis
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Author (Data of Publication) | Country | Year (s) of Sample Collections | Genotyping Method | Nº of Genotyped Samples | Vaccine Introduction Period a |
---|---|---|---|---|---|
Naficy A.B., et al. [19] | Egypt | 1995–1996 | RT-PCR | 46 | Before |
Allayeh A.K., et al. [20] | Egypt | 2015–2016 | RT-PCR | 37 | Before |
Saudy N., et al. [21] | Egypt | 2010–2012 | Multiplex RT-PCR | 45 | Before |
Elnady H.G., et al. [22] | Egypt | 2012–2012 | RT-PCR | 53 | Before |
Matson D.O., et al. [23] | Egypt | 2000–2002 | Nested RT-PCR | 243 | Before |
Ahmed S.F., et al. [24] | Egypt | 2004–2007 | Nested, multiplex RT-PCR | 164 | Before |
Benhafid M., et al. [25] | Morocco | 2006–2007 | RT-PCR | 134 | Before |
Benhafid M., et al. [26] | Morocco | 2006–2009 | Semi-nested, multiplex RT-PCR | 548 | Before |
El Qazoui M., et al. [27] | Morocco | 2011 | Multiplex RT-PCR | 89 | After |
Chouikha A., et al. [28] | Tunisia | 2005–2007 | Semi-nested, multiplex RT-PCR | 323 | Before |
Trabelsi A., et al. [29] | Tunisia | 2000–2003 | Semi-nested multiplex RT-PCR | 63 | Before |
Soltani M., et al. [30] | Tunisia | 2009–2011 | Semi-nested, multiplex RT-PCR | 188 | Before |
Chouikha A., et al. [31] | Tunisia | 2005–2007 | Semi-nested, multiplex RT-PCR | 180 | Before |
Moussa A., et al. [32] | Tunisia | 2009–2014 | Semi-nested RT-PCR | 270 | Before |
Bennour H., et al. [33] | Tunisia | 2015–2017 | Multiplex RT-PCR | 72 | Before |
Agbla J.M., et al. [34] | Benin | 2016–2018 | Multiplex RT-PCR | 186 | Before |
Steele A.D., et al. [35] | Burkina Faso | 1994 | RT-PCR | 36 | Before |
Bonkoungou I.J., et al. [36] | Burkina Faso | 2008–2010 | Semi-nested multiplex RT-PCR | 140 | Before |
Rönnelid Y., et al. [37] | Burkina Faso | 2015–2015 | Multiplex RT-PCR | 20 | After |
Nordgren J., et al. [38] | Burkina Faso | 2010 | Semi-nested, multiplex RT-PCR | 56 | Before |
Nordgren J., et al. [10] | Burkina Faso | 2009–2010 | Semi-nested, multiplex RT-PCR | 100 | Before |
Bonkoungou I.J.O., et al. [39] | Burkina Faso | 2012–2013 | RT-PCR | 67 | Before |
Armah G.E., et al. [40] | Ghana | 1999 | RT-PCR | 46 | Before |
Asmah R.H., et al. [41] | Ghana | 1998 | Semi-nested, multiplex RT-PCR | 50 | Before |
Binka F.N., et al. [42] | Ghana | 1998–2020 | Semi-nested PCR | 238 | Before |
Enweronu-Laryea C.C., et al. [43] | Ghana | 2007–2011 | RT-PCR | 876 | Before |
Lartey B.L., et al. [44] | Ghana | 2009–2016 | RT-PCR | 1363 | Before and After |
Letsa V., et al. [45] | Ghana | 2014–2016 | Semi-nested, multiplex RT-PCR | 136 | After |
Damanka S., et al. [46] | Ghana | 2004–2005 | RT-PCR | 70 | Before |
Nielsen N.M., et al. [47] | Guinea-Bissau | 2002 | Multiplex RT-PCR | 104 | Before |
Boni-Cisse C., et al. [48] | Ivory Coast | 2010–2013 | Multiplex RT-PCR | 186 | Before |
Page A.L., et al. [49] | Niger | 2010–2013 | RT-PCR | 449 | Before |
Audu R., et al. [50] | Nigeria | 1996–1997 | RT-PCR | 23 | Before |
Ianiro G., et al. [51] | Nigeria | 2013 | nested RT-PCR | 66 | Before |
Ayolabi C.I. [52] | Nigeria | 2007–2008 | RT-PCR | 58 | Before |
Uzoma E.B., et al. [53] | Nigeria | 2012–2013 | Nested, multiplex RT-PCR | 49 | Before |
Japhet M.O., et al. [54] | Nigeria | 2012–2013 | Semi-nested, multiplex RT-PCR | 49 | Before |
Amadu D.O., et al. [55] | Nigeria | 2013–2014 | Multiplex RT-PCR | 25 | Before |
Jere K.C., et al. [56] | Sierra Leone | 2005 | RT-PCR | 43 | Before |
Armah G.E., et al. [57] | Burkina Faso; Ivory Coast; Ghana, Nigeria, Cameroon. | 1996–2000 | RT-PCR | 925 | Before |
Esteves A., et al. [15] | Angola | 2012–2013 | Semi-nested, multiplex RT-PCR | 116 | Before |
Gasparinho C, et al. [9] | Angola | 2012–2013 | Semi-nested, multiplex RT-PCR | 72 | Before |
Esona M.D., et al. [58] | Cameroon | 1999–2000 | RT-PCR | 89 | Before |
Boula A., et al. [59] | Cameroon | 2007–2012 | Semi-nested, multiplex RT-PCR | 898 | Before |
Ndze V.N., et al. [60] | Cameroon | 2010–2011 | RT-PCR | 135 | Before |
Banga-Mingo V., et al. [61] | CAR | 2011–2013 | Multiple RT-PCR | 160 | Before |
Moure U.A.E., et al. [62] | CAR | 2014–2016 | Semi-nested, multiplex RT-PCR | 100 | Before |
Mayindou G., et al. [63] | Congo | 2012–2013 | RT-PCR | 219 | Before |
Kabue J.P., et al. [64] | DRC | 2003–2005 | RT-PCR | 119 | Before |
Pukuta E.S., et al. [65] | DRC | 2009–2012 | Multiplex RT-PCR | 330 | Before |
Istrate C., et al. [66] | São Tome and Principe | 2011 | Semi-nested, multiplex RT-PCR | 83 | Before |
Abebe A., et al. [67] | Ethiopia | 2007–2012 | Semi-nested, multiplex RT-PCR | 215 | Before |
Gelaw A., et al. [68] | Ethiopia | 2015–2016 | RT-PCR | 125 | After |
Nyangao J., et al. [69] | Kenya | 2000–2002 | Nested RT-PCR | 108 | Before |
Wandera E.A., et al. [70] | Kenya | 2009–2014 | Semi-nested, multiplex RT-PCR | 429 | Before |
Raini S.K., et al. [71] | Kenya | 2012–2013 | Nested RT-PCR | 30 | Before |
Kiulia N.M., et al. [72] | Kenya | 2009–2011 | RT-PCR | 157 | Before |
Wandera E.A., et al. [73] | Kenya | 2011–2016 | Semi-nested, multiplex RT-PCR | 61 | Before and After |
Cunliffe N.A., et al. [74] | Malawi | 1997–1998 | Semi-nested, multiplex RT-PCR | 100 | Before |
Cunliffe N.A., et al. [75] | Malawi | 1997–1999 | Multiplex RT-PCR | 414 | Before |
Cunliffe N.A., et al. [76] | Malawi | 1997–1999 | RT-PCR | 1130 | Before |
Turner A., et al. [77] | Malawi | 2008–2009 | Semi-nested, multiplex RT-PCR | 220 | Before |
João E.D., et al. [78] | Mozambique | 2015–2019 | RT-PCR | 650 | Before and After |
João E.D., et al. [12] | Mozambique | 2012–2013 | Semi-nested, multiplex RT-PCR | 157 | Before |
Chissaque A., et al. [79] | Mozambique | 2015–2019 | RT-PCR | 152 | Before and After |
Manjate F., et al. [80] | Mozambique | 2008–2012 2016–2019 | Semi-nested, multiplex RT-PCR | 291 | Before and After |
Hokororo A., et al. [81] | Tanzania | 2010–2012 | Multiplex RT-PCR | 100 | Before |
Odiit A., et al. [82] | Uganda | 2006–2012 | Semi-nested, RT-PCR | 354 | Before |
Bwogi J., et al. [83] | Uganda | 2012–2013 | Nested RT-PCR | 204 | Before |
Simwaka J., et al. [84] | Zambia | 2016 | RT-PCR | 116 | After |
Mukaratirwa A., at al. [85] | Zimbabwe | 2008–2016 | RT-PCR | 1096 | Before and After |
Mukaratirwa A., et al. [86] | Zimbabwe | 2008–2011 | RT-PCR | 127 | Before |
Mokomane M., et al. [87] | Botswana | 2011–2018 | Multiplex RT-PCR | 284 | Before and After |
Page N., et al. [88] | Namibia | 1998–1999 | RT-PCR | 113 | Before |
Seheri L.M., et al. [89] | South Africa | 2003–2006 | Semi-nested, RT-PCR | 648 | Before |
Genotype | Positive Cases | African Regions—Prevalence (%) | |||||
---|---|---|---|---|---|---|---|
North | West | Central | East | South | Global [95% CI] | ||
G1 | 5352 | 40.5 | 24.8 | 34.3 | 29.8 | 34.9 | 30.7 [24.2–37.3] |
G2 | 2588 | 16.2 | 18.5 | 18.1 | 10 | 14.7 | 14.9 [11.0–18.7] |
G3 | 1899 | 11.5 | 12.9 | 8.4 | 8.4 | 20.0 | 10.9 [5.6–16.2] |
G4 | 282 | 4.9 | 0.9 | 1.8 | 1.2 | - | 1.6 [0–4.2] |
G5 | 2 | - | 0.02 | 0.04 | - | - | 0.01 [0–0.1] |
G6 | 107 | - | 1.2 | 1.7 | 0.05 | - | 0.6 [0–2.4] |
G8 | 1042 | 0.2 | 2.4 | 6.9 | 11.4 | 3.3 | 6.0 [1.1–10.9] |
G9 | 2086 | 9.1 | 8.3 | 3.7 | 19.0 | 14.5 | 12.0 [5.4–18.6] |
G10 | 140 | - | 2.5 | 0.3 | - | - | 0.80 [0–10.6] |
G12 | 1261 | 0.8 | 10.7 | 9.3 | 6.7 | 3.3 | 7.2 [2.7–11.8] |
P (4) | 2390 | 338 | 672 | 213 | 1012 | 155 | 13.72 [10.62–16.82] |
P (6) | 4353 | 190 | 1559 | 902 | 1520 | 182 | 24.99 [12.35–37.64] |
P (8) | 7465 | 1329 | 1856 | 936 | 2770 | 574 | 42.86 [33.01–52,71] |
P (9) | 12 | 2 | 7 | 3 | - | - | 0.07 [0.01–0.12] |
P (10) | 7 | - | 6 | 1 | - | - | 0.04 [−0.28–0.36] |
P (11) | 30 | 29 | - | 1 | - | - | 0.17 [−4.95–5.29] |
P (14) | 1 | 1 | - | - | - | - | 0.01 [0.01] |
G1P[4] | 114 | 31 | 15 | 28 | 37 | 3 | 0.65 [0.1–1.2] |
G1P[6] | 742 | 53 | 218 | 202 | 215 | 54 | 4.26 [1.6–6.8] |
G1P[8] | 3745 | 811 | 614 | 526 | 1529 | 265 | 21.50 [12.9–30] |
G2P[4] | 1364 | 267 | 376 | 177 | 416 | 128 | 7.83 [5–10.6] |
G2P[6] | 709 | 40 | 306 | 205 | 132 | 26 | 4.07 [0.8–7.4] |
G2P[8] | 143 | 16 | 74 | 34 | 19 | - | 0.82 [0.06–1.6] |
G3P[4] | 292 | 26 | 112 | 2 | 142 | 10 | 1.68 [0.7–2.7] |
G3P[6] | 516 | 10 | 324 | 39 | 99 | 44 | 2.96 [0.3–5.5] |
G3P[8] | 815 | 209 | 62 | 52 | 337 | 155 | 4.68 [1.4–10.8] |
G4P[8] | 163 | 85 | 10 | 12 | 56 | - | 0.94 [−1.12- 3] |
G8P[4] | 238 | - | 7 | 9 | 211 | 11 | 1.37 [−0.68–3.41] |
G8P[6] | 551 | - | 32 | 120 | 390 | 9 | 3.16 [−0.79–7.12] |
G8P[8] | 104 | - | 14 | 19 | 56 | 15 | 0.60 [−0.06–1.26] |
G9P[4] | 125 | 1 | 36 | 2 | 83 | 3 | 0.72 [0.12–1.31] |
G9P[6] | 473 | 20 | 70 | 15 | 343 | 25 | 2.72 [0.49–4.94] |
G9P[8] | 1309 | 202 | 259 | 67 | 657 | 124 | 7.52 [3.3–11.73] |
G10P[6] | 110 | 110 | - | - | - | 0.63 [0.63] | |
G12P[6] | 389 | 13 | 68 | 78 | 210 | 20 | 2.23 [0.87–3.6] |
G12P[8] | 772 | 10 | 457 | 131 | 160 | 14 | 4.43 [0.69–8.17] |
Others * | 329 | 52 | 112 | 74 | 91 | - | 1.89 [0.62–3.15] |
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Miranda, S.; Tonin, F.S.; Pinto-Sousa, C.; Fortes-Gabriel, E.; Brito, M. Genetic Profile of Rotavirus Type A in Children under 5 Years Old in Africa: A Systematic Review of Prevalence. Viruses 2024, 16, 243. https://doi.org/10.3390/v16020243
Miranda S, Tonin FS, Pinto-Sousa C, Fortes-Gabriel E, Brito M. Genetic Profile of Rotavirus Type A in Children under 5 Years Old in Africa: A Systematic Review of Prevalence. Viruses. 2024; 16(2):243. https://doi.org/10.3390/v16020243
Chicago/Turabian StyleMiranda, Sandra, Fernanda S. Tonin, Carlos Pinto-Sousa, Elsa Fortes-Gabriel, and Miguel Brito. 2024. "Genetic Profile of Rotavirus Type A in Children under 5 Years Old in Africa: A Systematic Review of Prevalence" Viruses 16, no. 2: 243. https://doi.org/10.3390/v16020243
APA StyleMiranda, S., Tonin, F. S., Pinto-Sousa, C., Fortes-Gabriel, E., & Brito, M. (2024). Genetic Profile of Rotavirus Type A in Children under 5 Years Old in Africa: A Systematic Review of Prevalence. Viruses, 16(2), 243. https://doi.org/10.3390/v16020243