Human Astrovirus Outbreak in a Daycare Center and Propagation among Household Contacts
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Data Processing and Analysis
2.3. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Age | Affected | Total | AR | RR (95% CI) | |
---|---|---|---|---|---|
Daycare attenders | 0 year | 0 | 5 | 0% | NC |
1 year | 14 | 29 | 48.3% | 1 | |
2 years | 3 | 28 | 10.7% | 0.22 (0.07–0.69) | |
3 years | 1 | 9 | 11.1% | 0.23 (0.03–1.52) | |
Adults | 2 | 5 | 40% | 0.56 (0.26–1.23) | |
Household contacts | 0–5 | 6 | 22 | 27.3% | 0.82 (0.30–2.20) |
6–10 years | 5 | 15 | 33.3% | 1 | |
11–25 years | 0 | 11 | 0% | NC | |
26–35 years | 5 | 42 | 11.9% | 0.36 (0.12–1.06) | |
36–45 years | 13 | 72 | 18.1% | 0.54 (0.23–1.29) | |
46–55 years | 0 | 5 | 0% | NC | |
Total contacts * | 29 | 169 | 17.2% |
Sample ID | Clinical Case (Yes/No) | Age | Virus | Date of Symptom onset |
---|---|---|---|---|
1 | No | 14 months | NoV GI | – |
2 | No | 14 months | HAstV-8 | – |
3 | No | 9 months | HAstV-4 | – |
4 | Yes | 17 months | HAstV-4 | 28/2/17 |
5 | Yes | 16 months | HAstV-4 | 6/3/17 |
6 | Yes | 14 months | Astrovirus non-typeable | 6/3/17 |
7 | Yes | 22 months | Astrovirus non-typeable | 7/3/17 |
8 | No | 21 months | HAstV-4 | – |
9 | Yes | 21 months | HAstV-4 | 4/3/17 |
10 | Yes | 36 months | Astrovirus non-typeable | 6/3/17 |
11 | Yes | 32 years | NoV GI | 10/3/17 |
12 | No | 34 years | HAstV-8 | – |
Status of Attenders | Household Contacts | |||
---|---|---|---|---|
Affected | Exposed | AR | RR (95% CI) | |
Affected | 26 | 35 * | 74.3% | 30.95 (9.95–96.27) |
Non-affected | 3 | 125 | 2.4% | 1 |
Age of Daycare Center Attenders | Household Contacts | |||
---|---|---|---|---|
Affected | Total | AR | RR (95% CI) * | |
<1 year | 0 | 16 | 0% | 0.15 (0.01–2.40) |
1 year | 19 | 65 | 29.2% | 3.04 (1.51–6.12) |
2 years | 5 | 58 | 8.6% | 0.40 (0.16–0.99) |
3 years | 2 | 21 | 9.5% | 0.52 (0.13–2.04) |
Workers | 3 | 9 | 33.3% | 2.05 (0.76–5.51) |
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Parrón, I.; Plasencia, E.; Cornejo-Sánchez, T.; Jané, M.; Pérez, C.; Izquierdo, C.; Guix, S.; Domínguez, À.; on behalf of the Working Group for the Study of Acute Gastroenteritis Outbreaks in Catalonia. Human Astrovirus Outbreak in a Daycare Center and Propagation among Household Contacts. Viruses 2021, 13, 1100. https://doi.org/10.3390/v13061100
Parrón I, Plasencia E, Cornejo-Sánchez T, Jané M, Pérez C, Izquierdo C, Guix S, Domínguez À, on behalf of the Working Group for the Study of Acute Gastroenteritis Outbreaks in Catalonia. Human Astrovirus Outbreak in a Daycare Center and Propagation among Household Contacts. Viruses. 2021; 13(6):1100. https://doi.org/10.3390/v13061100
Chicago/Turabian StyleParrón, Ignacio, Elsa Plasencia, Thais Cornejo-Sánchez, Mireia Jané, Cristina Pérez, Conchita Izquierdo, Susana Guix, Àngela Domínguez, and on behalf of the Working Group for the Study of Acute Gastroenteritis Outbreaks in Catalonia. 2021. "Human Astrovirus Outbreak in a Daycare Center and Propagation among Household Contacts" Viruses 13, no. 6: 1100. https://doi.org/10.3390/v13061100
APA StyleParrón, I., Plasencia, E., Cornejo-Sánchez, T., Jané, M., Pérez, C., Izquierdo, C., Guix, S., Domínguez, À., & on behalf of the Working Group for the Study of Acute Gastroenteritis Outbreaks in Catalonia. (2021). Human Astrovirus Outbreak in a Daycare Center and Propagation among Household Contacts. Viruses, 13(6), 1100. https://doi.org/10.3390/v13061100