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The Interplay between Adeno-Associated Virus and Its Helper Viruses

Institute of Virology, University of Zurich, CH-8057 Zurich, Switzerland
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Viruses 2020, 12(6), 662; https://doi.org/10.3390/v12060662
Received: 30 May 2020 / Revised: 15 June 2020 / Accepted: 18 June 2020 / Published: 19 June 2020
(This article belongs to the Special Issue Viral Coinfection)
The adeno-associated virus (AAV) is a small, nonpathogenic parvovirus, which depends on helper factors to replicate. Those helper factors can be provided by coinfecting helper viruses such as adenoviruses, herpesviruses, or papillomaviruses. We review the basic biology of AAV and its most-studied helper viruses, adenovirus type 5 (AdV5) and herpes simplex virus type 1 (HSV-1). We further outline the direct and indirect interactions of AAV with those and additional helper viruses. View Full-Text
Keywords: adeno-associated virus; herpes simplex virus; adenovirus; viral coinfections; helper virus; viral vectors adeno-associated virus; herpes simplex virus; adenovirus; viral coinfections; helper virus; viral vectors
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MDPI and ACS Style

Meier, A.F.; Fraefel, C.; Seyffert, M. The Interplay between Adeno-Associated Virus and Its Helper Viruses. Viruses 2020, 12, 662. https://doi.org/10.3390/v12060662

AMA Style

Meier AF, Fraefel C, Seyffert M. The Interplay between Adeno-Associated Virus and Its Helper Viruses. Viruses. 2020; 12(6):662. https://doi.org/10.3390/v12060662

Chicago/Turabian Style

Meier, Anita F., Cornel Fraefel, and Michael Seyffert. 2020. "The Interplay between Adeno-Associated Virus and Its Helper Viruses" Viruses 12, no. 6: 662. https://doi.org/10.3390/v12060662

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