Virosaurus A Reference to Explore and Capture Virus Genetic Diversity
Abstract
:1. Introduction
2. Materials and Methods
2.1. Data Collection and Cleaning Up of Viral Sequences
2.2. Generation of Complete Virus Sequence Dataset
2.3. Clustering
2.4. Generation of Virus Genes Dataset
2.5. Clinical Annotation
2.6. FASTA Format
2.7. Evaluation on Clinical Samples
3. Results
3.1. Data Collection
3.2. Clinical Annotation
3.3. Clustering
3.4. Reducing False Negatives in Virus Detection
3.5. Validation on Clinical Samples
3.6. Virosaurus Availability and Updates
4. Discussion
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
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Gleizes, A.; Laubscher, F.; Guex, N.; Iseli, C.; Junier, T.; Cordey, S.; Fellay, J.; Xenarios, I.; Kaiser, L.; Mercier, P.L. Virosaurus A Reference to Explore and Capture Virus Genetic Diversity. Viruses 2020, 12, 1248. https://doi.org/10.3390/v12111248
Gleizes A, Laubscher F, Guex N, Iseli C, Junier T, Cordey S, Fellay J, Xenarios I, Kaiser L, Mercier PL. Virosaurus A Reference to Explore and Capture Virus Genetic Diversity. Viruses. 2020; 12(11):1248. https://doi.org/10.3390/v12111248
Chicago/Turabian StyleGleizes, Anne, Florian Laubscher, Nicolas Guex, Christian Iseli, Thomas Junier, Samuel Cordey, Jacques Fellay, Ioannis Xenarios, Laurent Kaiser, and Philippe Le Mercier. 2020. "Virosaurus A Reference to Explore and Capture Virus Genetic Diversity" Viruses 12, no. 11: 1248. https://doi.org/10.3390/v12111248