Bovine Pestivirus Heterogeneity and Its Potential Impact on Vaccination and Diagnosis
Abstract
:1. Bovine Pestiviruses
2. Impact and Control of Bovine Pestiviruses
3. Immunity to Bovine Pestiviruses
4. Cross-Protection between Bovine Pestiviruses
5. Vaccination against Bovine Pestiviruses
5.1. Modified Live Virus Vaccines
5.2. Inactivated Vaccines
5.3. Differentiation of Infection from Vaccination (DIVA)
5.4. Sub-Unit and Next-Generation Vaccines
6. Diagnosis of Bovine Pestiviruses
7. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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MH379638.1 | M96687 | KX987157 | KR866116 | LC089876 | JN400273 | JQ799141 | AF502399 | KJ000672 | MH231148 | KY683847 | FJ040215 | JQ612704 | |
MH379638.1 BVDV-1a GB Ho916 | 100 | 75.6 | 73.3 | 73.7 | 71.9 | 69.6 | 66.3 | 58.5 | 56.7 | 60.4 | 54.1 | 52.6 | 53 |
M96687 BVDV-1b OSLOSS | 84.5 | 100 | 69 | 72.3 | 72.3 | 69.7 | 64.9 | 57.2 | 56.1 | 59.4 | 52.8 | 52.4 | 52.4 |
KX987157 BVDV-1f SLO | 82.6 | 79.3 | 100 | 72.2 | 75.2 | 73.7 | 71.1 | 59.6 | 58.1 | 61.5 | 56.7 | 54.4 | 56.7 |
KR866116 BVDV-1m CN | 84.1 | 81.2 | 85.2 | 100 | 70.7 | 74.4 | 66.7 | 55.9 | 57.4 | 59.6 | 57.4 | 56.3 | 58.1 |
LC089876 BVDV-1n JP | 79.6 | 81.2 | 83 | 81.5 | 100 | 67.4 | 68.5 | 58.5 | 57 | 58.5 | 55.9 | 55.2 | 54.4 |
JN400273 BVDV-1q SD0803 pig | 82.2 | 81.9 | 84.1 | 83.7 | 78.9 | 100 | 65.9 | 58.1 | 59.3 | 60.7 | 55.2 | 53.3 | 55.9 |
JQ799141 BVDV-1u Yak CN | 78.5 | 77.1 | 81.1 | 80.4 | 79.6 | 81.9 | 100 | 58.1 | 60.4 | 63 | 52.6 | 52.2 | 52.6 |
AF502399 BVDV-2a NY-93 | 71.9 | 70.5 | 73.3 | 72.2 | 68.1 | 74.4 | 75.2 | 100 | 80.6 | 80.6 | 52.2 | 54.1 | 51.1 |
KJ000672 BVDV-2b SD1301 | 70.4 | 67.5 | 71.1 | 71.5 | 66.3 | 73.7 | 74.1 | 88.4 | 100 | 81 | 50.7 | 53 | 50.4 |
MH231148 BVDV-2c 12-149150 | 72.2 | 70.5 | 73.3 | 73.3 | 68.1 | 73.7 | 77 | 90.7 | 87.7 | 100 | 53.7 | 54.4 | 53 |
KY683847 BVDV-3 BRA Bos Ind | 67 | 67.2 | 71.9 | 71.9 | 71.1 | 70.4 | 67.8 | 65.9 | 65.2 | 66.3 | 100 | 90 | 94.1 |
FJ040215 BVDV-3 Thai KK | 68.5 | 67.9 | 71.9 | 70.7 | 73 | 70 | 68.5 | 67.8 | 67 | 67.4 | 94.8 | 100 | 86.2 |
JQ612704 BVDV-3 IT | 66.3 | 66.4 | 71.1 | 72.2 | 69.6 | 71.1 | 68.1 | 65.6 | 65.9 | 65.6 | 97 | 92.6 | 100 |
MH379638.1 | M96687 | KX987157 | KR866116 | LC089876 | JN400273 | JQ799141 | AF502399 | KJ000672 | MH231148 | KY683847 | FJ040215 | JQ612704 | |
MH379638.1 BVDV-1a GB Ho916 | 100 | 97.5 | 97.4 | 97.4 | 97.4 | 97.4 | 94 | 91.9 | 91.1 | 92.1 | 92.4 | 91.8 | 92.2 |
M96687 BVDV-1b OSLOSS | 99.4 | 100 | 97.4 | 97.8 | 97.8 | 97.8 | 94.3 | 92.1 | 90.6 | 91.9 | 92.5 | 91.9 | 92.4 |
KX987157 BVDV-1f SLO | 99.4 | 99.4 | 100 | 98.1 | 97.4 | 98 | 94.4 | 92.1 | 90.8 | 91.9 | 92.5 | 91.9 | 92.4 |
KR866116 BVDV-1m CN | 99.4 | 99.4 | 99.4 | 100 | 97.8 | 98.2 | 94 | 92.7 | 91.4 | 92.5 | 92.4 | 91.5 | 92.2 |
LC089876 BVDV-1n JP | 99.4 | 99.4 | 99.4 | 99.4 | 100 | 97.7 | 94 | 91.8 | 90.3 | 91.7 | 92.4 | 91.9 | 91.9 |
JN400273 BVDV-1q SD0803 pig | 99.1 | 99.4 | 99 | 99.1 | 99.1 | 100 | 94.6 | 91.7 | 90.5 | 91.5 | 92.4 | 91.7 | 92.2 |
JQ799141 BVDV-1u Yak CN | 98.2 | 98.2 | 98.1 | 98 | 98 | 98 | 100 | 90.6 | 89.5 | 89.9 | 91.5 | 91.4 | 91.5 |
AF502399 BVDV-2a NY-93 | 98.2 | 98 | 98.4 | 98.2 | 98 | 97.7 | 97.1 | 100 | 97.5 | 98.1 | 91.7 | 90.9 | 91.5 |
KJ000672 BVDV-2b SD1301 | 97.5 | 97.5 | 98 | 97.8 | 97.5 | 97.2 | 96.3 | 99 | 100 | 97.7 | 90.3 | 89.9 | 90.8 |
MH231148 BVDV-2c 12-149150 | 98.1 | 97.8 | 98.2 | 98.1 | 97.8 | 97.5 | 96.9 | 99.6 | 99.1 | 100 | 91.1 | 90.3 | 91.2 |
KY683847 BVDV-3 BRA Bos Ind | 97.2 | 97.2 | 96.9 | 97.4 | 97.2 | 97.2 | 96.6 | 96.6 | 95.9 | 96.5 | 100 | 98.5 | 99.6 |
FJ040215 BVDV-3 Thai KK | 97.2 | 97.2 | 96.9 | 97.2 | 97.2 | 96.9 | 96.6 | 96.3 | 95.9 | 96.2 | 99.3 | 100 | 98.4 |
JQ612704 BVDV-3 IT | 97.2 | 97.2 | 96.9 | 97.4 | 96.9 | 97.2 | 96.6 | 96.6 | 96.2 | 96.5 | 99.7 | 99.3 | 100 |
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Riitho, V.; Strong, R.; Larska, M.; Graham, S.P.; Steinbach, F. Bovine Pestivirus Heterogeneity and Its Potential Impact on Vaccination and Diagnosis. Viruses 2020, 12, 1134. https://doi.org/10.3390/v12101134
Riitho V, Strong R, Larska M, Graham SP, Steinbach F. Bovine Pestivirus Heterogeneity and Its Potential Impact on Vaccination and Diagnosis. Viruses. 2020; 12(10):1134. https://doi.org/10.3390/v12101134
Chicago/Turabian StyleRiitho, Victor, Rebecca Strong, Magdalena Larska, Simon P. Graham, and Falko Steinbach. 2020. "Bovine Pestivirus Heterogeneity and Its Potential Impact on Vaccination and Diagnosis" Viruses 12, no. 10: 1134. https://doi.org/10.3390/v12101134