Block-And-Lock Strategies to Cure HIV Infection
Abstract
1. Introduction
2. HIV Transcription and Silencing
3. Block-And-Lock Strategies
3.1. Tat Inhibition by Didehydro-Cortistatin A
3.2. LEDGINs
3.3. FACT Inhibition by Curaxin CBL0100
3.4. RNA-Induced Epigenetic Silencing
3.5. HSP90 Inhibitors
3.6. Jak-STAT Inhibitors
3.7. BRD4 Modulators
3.8. mTOR Inhibitors
3.9. Kinase Inhibitors
3.10. Triptolide
4. Discussion
Author Contributions
Funding
Conflicts of Interest
References
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Vansant, G.; Bruggemans, A.; Janssens, J.; Debyser, Z. Block-And-Lock Strategies to Cure HIV Infection. Viruses 2020, 12, 84. https://doi.org/10.3390/v12010084
Vansant G, Bruggemans A, Janssens J, Debyser Z. Block-And-Lock Strategies to Cure HIV Infection. Viruses. 2020; 12(1):84. https://doi.org/10.3390/v12010084
Chicago/Turabian StyleVansant, Gerlinde, Anne Bruggemans, Julie Janssens, and Zeger Debyser. 2020. "Block-And-Lock Strategies to Cure HIV Infection" Viruses 12, no. 1: 84. https://doi.org/10.3390/v12010084
APA StyleVansant, G., Bruggemans, A., Janssens, J., & Debyser, Z. (2020). Block-And-Lock Strategies to Cure HIV Infection. Viruses, 12(1), 84. https://doi.org/10.3390/v12010084