Airborne Transmission of a Serotype 4 Fowl Adenovirus in Chickens
AbstractSerotype 4 fowl adenovirus (FAdV-4) is the main pathogen for hydropericardium syndrome (HPS) in chickens. It has caused major economic losses in the global poultry industry. Currently, FAdV-4′s transmission routes in chickens remain unclear. Here we investigate the airborne transmission routes of FAdV-4 in chickens. A total of 45 ten-day-old chickens were equally divided into three groups (infected group/isolator A, airborne group/isolator B, and control group/isolator C). Of note, isolators A and B were connected by a leak-free pipe. The results showed that the virus could form a viral aerosol, detected in isolators two days post infection (dpi). The viral aerosol reached a peak at 4 dpi in the infected group. Healthy chickens in the airborne group were infected by the virus at 8 dpi. The chickens of the airborne group demonstrated subclinical symptoms capable of shedding the virus for some time. This finding suggests that FAdV-4 can be efficiently transmitted among chickens by aerosol transmission. These findings have significant implications for developing strategies to control this infectious disease epidemic. View Full-Text
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Li, G.; Yu, G.; Niu, Y.; Cai, Y.; Liu, S. Airborne Transmission of a Serotype 4 Fowl Adenovirus in Chickens. Viruses 2019, 11, 262.
Li G, Yu G, Niu Y, Cai Y, Liu S. Airborne Transmission of a Serotype 4 Fowl Adenovirus in Chickens. Viruses. 2019; 11(3):262.Chicago/Turabian Style
Li, Gang; Yu, Guanliu; Niu, Yujuan; Cai, Yumei; Liu, Sidang. 2019. "Airborne Transmission of a Serotype 4 Fowl Adenovirus in Chickens." Viruses 11, no. 3: 262.
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