Next Article in Journal
Murine Coronavirus Cell Type Dependent Interaction with the Type I Interferon Response
Next Article in Special Issue
All Known Human Rhinovirus Species Are Present in Sputum Specimens of Military Recruits During Respiratory Infection
Previous Article in Journal
Revisiting Plus-Strand DNA Synthesis in Retroviruses and Long Terminal Repeat Retrotransposons: Dynamics of Enzyme: Substrate Interactions
Previous Article in Special Issue
Seroconversion to HCoV-NL63 in Rhesus Macaques
Open AccessReview

WU Polyomavirus (WUPyV): A Recently Detected Virus Causing Respiratory Disease?

1
Division of Virology, Department of Medical Microbiology, University Hospital Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
2
Deparment of Pediatrics, University Hospital Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
3
Department of Infection Control and Infectious Diseases, University Hospital Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
*
Author to whom correspondence should be addressed.
Viruses 2009, 1(3), 678-688; https://doi.org/10.3390/v1030678
Received: 20 August 2009 / Revised: 19 October 2009 / Accepted: 4 November 2009 / Published: 4 November 2009
(This article belongs to the Special Issue Newly Identified Respiratory Viruses)
The WU polyomavirus (WUPyV) is a novel member of the family Polyomaviridae recently detected in respiratory tract specimens by shotgun sequencing. Intriguingly, viral genome has been detected in 0.4% to 11.5% of respiratory tract specimens from children with respiratory disease. The levels of co-infection with established respiratory viruses were in the range between 30.8% and 91.7%. Moreover, some studies report detection of WUPyV in stool or serum. So far, WUPyV infections can not be distinguished from other viral infections by means of clinical symptoms. Respiratory tract disease like pneumonia or bronchitis is frequently observed in patients harbouring WUPyV. Detection of viremia suggests systemic infections. However, the available data do not prove WUPyV to be a human pathogen. Further investigations are necessary. View Full-Text
Keywords: respiratory tract disease; infection; novel virus; Polyomaviridae; WUPyV respiratory tract disease; infection; novel virus; Polyomaviridae; WUPyV
MDPI and ACS Style

Kleines, M.; Häusler, M.; Krüttgen, A.; Scheithauer, S. WU Polyomavirus (WUPyV): A Recently Detected Virus Causing Respiratory Disease? Viruses 2009, 1, 678-688.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop