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A(H5N1) Virus Evolution in South East Asia

Institut Pasteur du Cambodge, Virology Unit, 5 Monivong boulevard, PO Box 983, Phnom Penh, Cambodia
National Veterinary Research Institute (NaVRI)/ Phum Trea, Sals Street # 371, Phnom Penh, Cambodia
Author to whom correspondence should be addressed.
Viruses 2009, 1(3), 335-361;
Received: 6 July 2009 / Revised: 2 September 2009 / Accepted: 2 October 2009 / Published: 6 October 2009
(This article belongs to the Special Issue Influenza: Pandemics and Vaccinations)
Highly Pathogenic Avian Influenza (HPAI) H5N1 virus is an ongoing public health and socio-economic challenge, particularly in South East Asia. H5N1 is now endemic in poultry in many countries, and represents a major pandemic threat. Here, we describe the evolution of H5N1 virus in South East Asia, the reassortment events leading to high genetic diversity in the region, and factors responsible for virus spread. The virus has evolved with genetic variations affecting virulence, drug-resistance, and adaptation to new host species. The constant surveillance of these changes is of primary importance in the global efforts of the scientific community. View Full-Text
Keywords: avian influenza; H5N1 virus; evolution; South East Asia avian influenza; H5N1 virus; evolution; South East Asia
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MDPI and ACS Style

Gutiérrez, R.A.; Naughtin, M.J.; Horm, S.V.; San, S.; Buchy, P. A(H5N1) Virus Evolution in South East Asia. Viruses 2009, 1, 335-361.

AMA Style

Gutiérrez RA, Naughtin MJ, Horm SV, San S, Buchy P. A(H5N1) Virus Evolution in South East Asia. Viruses. 2009; 1(3):335-361.

Chicago/Turabian Style

Gutiérrez, Ramona A., Monica J. Naughtin, Srey V. Horm, Sorn San, and Philippe Buchy. 2009. "A(H5N1) Virus Evolution in South East Asia" Viruses 1, no. 3: 335-361.

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