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Viruses 2009, 1(3), 1351-1363;

H5N1 Virus Evolution in Europe—An Updated Overview

OIE, FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell’Università 10, 35020 Legnaro, PD, Italy
Author to whom correspondence should be addressed.
Received: 18 September 2009 / Revised: 28 November 2009 / Accepted: 18 December 2009 / Published: 23 December 2009
(This article belongs to the Special Issue Influenza: Pandemics and Vaccinations)
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Since its emergence in South East Asia in 2003, Highly Pathogenic Avian Influenza (HPAI) A/H5N1 has reportedly caused outbreaks in poultry and/or wild birds in 62 countries, of which 24 were in Europe. Interestingly, out of the many genetic clades circulating in Asia, the westward spread of HPAI A/H5N1 to Central Asia, the Middle East, Europe and Africa was dominated by one single clade, namely clade 2.2. In this paper, we review and update through phylogenetic and gene migrational analysis the information concerning the evolution and the molecular epidemiology of HPAI A/H5N1 on the European continent. View Full-Text
Keywords: Europe; H5N1; avian influenza Europe; H5N1; avian influenza

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Cattoli, G.; Fusaro, A.; Monne, I.; Capua, I. H5N1 Virus Evolution in Europe—An Updated Overview. Viruses 2009, 1, 1351-1363.

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