Henipaviruses Employ a Multifaceted Approach to Evade the Antiviral Interferon Response
Abstract
:1. Overview of the Henipavirus genus
2. Henipavirus P gene products
mRNA editing
3. Domain structure and localization of the P, V and W proteins
3.1. The C protein
Inhibition of interferon synthesis by henipavirus V and W proteins
3.2. Interaction of the V protein with RNA helicases, mda-5 and LGP2
3.3. W-mediated inhibition of IFN production from the nucleus
4. Inhibition of interferon signaling by henipavirus P, V and W proteins
4.1. STAT re-localization and inhibition of IFN-activated phosphorylation
4.2. Interaction with STAT1 and STAT2
5. The unexplored role of the C protein
6. Conclusions
Acknowledgments
References
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Shaw, M.L. Henipaviruses Employ a Multifaceted Approach to Evade the Antiviral Interferon Response. Viruses 2009, 1, 1190-1203. https://doi.org/10.3390/v1031190
Shaw ML. Henipaviruses Employ a Multifaceted Approach to Evade the Antiviral Interferon Response. Viruses. 2009; 1(3):1190-1203. https://doi.org/10.3390/v1031190
Chicago/Turabian StyleShaw, Megan L. 2009. "Henipaviruses Employ a Multifaceted Approach to Evade the Antiviral Interferon Response" Viruses 1, no. 3: 1190-1203. https://doi.org/10.3390/v1031190
APA StyleShaw, M. L. (2009). Henipaviruses Employ a Multifaceted Approach to Evade the Antiviral Interferon Response. Viruses, 1(3), 1190-1203. https://doi.org/10.3390/v1031190